"Capecitabine": aʻo no ka hoʻohana 'ana, maoli counterparts, hookuu palapala, i ka Hookah. "Capecitabine-aku": olelo

Capecitabine (. Lakina Capecitabinum) - he waiwai ia mea he fluoropyrimidine carbamate derivative. Ka mea, no a hiki i ka pae ana o antimetabolites - manaʻo i huiʻia hiki ke inhibit ulu o malignant hikoko. Ke kuleana i loko o ia mau waiwai originated i ka 1960 g. I loaa mai ma ka haʻawina mua maikaʻi i nā hualoaʻa ma kaʻiole. Kekahi manawa ma hope, ka mea iʻike kona laulā ma ka iapaau ana o kekahi maʻi 'aʻai ka maʻi i loko o kānaka.

I kēia lā, he nui anticancer ai 'i loaʻa i ka hana waiwai capecitabine. Reviews o na mea he nui nā mea maʻi e olelo aku e pili ana i ka pomaikai o ke noi ana o ia mau hana i loko o anticancer Inc.

Pākōlea a me ka waiwai

Haʻilula capecitabine - 5'-deoxy-5-fluoro-N - [(pentyloxy) carbonyl] cytidine. Antimetabolites Nine Inch pūʻulu ua poe ma ka helu o ka waiwai i mea like i loko o ka aoao maoli i na nā huahana o ka pūnao (pūnao) kanaka. e hiki ke komo i loko o metabolic reactions, a hoʻomaʻa ia lakou, e 'ūlōlohi mai ana i kekahi o ka biochemical keʻano o ka hanaʻana lakou. Pela ka mea, he malfunction i nuiʻeho keena a me inhibition o ko lākou ulu ka wā hoʻohana 'ana i hoomakaukau ana me ka nānā' waiwai capecitabine. Reviews o kanaka e kamailio ana hoemi i ka nui o ka hikoko. Kēiaʻano papa hana o ka 'ana ua kapaia cytostatic.

I kŰia mau mea ae i ka hoʻohana 'ana o ka waiwai antimetabolitnyh ia i loko o anticancer Inc. ko lakou ai e ku e ia hopenaʻoi loa malignant hikoko o ka gastrointestinal'āpana a me mammary glands. Ma keia hihia, he hopena maikaʻi haawi o ka monotherapy, a me ka hui pu ana, a me nā konohiki. I ka lā, ma ke kumu o Anati-metabolites hana oi ma mua o 800 huahana, akā nō mau i ka huli 'ana no ka hou pūʻulu o nā hui.

ʻano papa hana o ka hana

Capecitabine ho'ā hope ia lŘlŘ i loko o nā nā'aʻaʻa o kaʻeho, ma hope i ka mea i hoʻomaka e kulia konaʻawahia kanawai ma na keena (cytotoxicʻano papa hana). Keia waiwai ua komo i loko o ka pūnao o ka naoh, a hiki aku i ka mea i ka mea ola, a me kaʻeho aeee i hoohuliia mai i loko o cytotoxic analogs. Pela ka mea, he 'aʻe' hoʻomakaʻia waiwai pono no ka DNA hoʻololi kemikala, a, nolaila, ke puunaue kaʻina.

Mai na keena oki, e hoomahuahua i ko lakou helu. Ma kekahi ha i, aia no he "hakahaka" o kekahi i kekahi waiwai, a ma ke kumuʻiʻo hoʻololi kemikala ka meaʻehaʻeha wā lawe ai 'ia me ka nānā capecitabine hui. Alakaʻi wehewehe i au mamuli keia kaʻina.

Keʻano papa hana o keia loli minimizes ka manawa kūpono o ka poho i ola keena. Capecitabine Ua oi i kia ma kaʻeho ia iho, ma mua o loko o ka puni nā'aʻaʻa. Oia ka hiʻona mea emi mai nā palapala i ke kino o kekahi kanaka e, ua malamaia lakou nei, no ka lāʻau ma muli o ka waiwai capecitabine. Na Ke Kumu no ka hoʻohana i ke heluhelu loaa dala ma ka pololei i ho'ākāka 'nā māhele i i manao ia e ka hele kauka.

E hoʻokaʻaʻike waiwai i loko o ke kino

Ma ka loaʻa 'capecitabine o kona kokololio omo i loko o ka gastrointestinal'āpana. Inā 'oe e ai ai i keia manawa, ke kaʻina hana, e' ūlōlohi mai ana. No laila, ma muli o ka? Eaia antimetabolite ai 'ua lawe mai ma hope, inu. Hou hou 'ia lŘlŘ ma ke akepaʻa waiwai, he kekahi nui o ka capecitabine a me kona metabolites nakinaki i nā polokina (e laʻa me, albumin). Ka piko lāʻau lapaʻau pae i hiki aku ma hope o 1.5 -3 hola ma hope o ka lāʻau 'palapala noi. Keia olelo i ka lāʻau "Capecitabine" ke aʻoʻia. Analogs i like pharmacokinetics.

Ka hapa nui o ka waiwai a ua excreted i loko o ka mimi, ma lalo - a me na feces. Hoʻi,ʻaʻole wale na lau i ke kino capecitabine ua hoʻololiʻia (ma kahi o 3%), akā, kona nā mea loaʻa. Kekahi o ia i metabolized i emi hana i huiʻia. Ka noho, a me ka hou 'ana o capecitabine i loko o ke kino e ole loli ana i hoohanau, makahiki, heihei.

I ka lawelawe?

Capecitabine i loko o nā mea haʻilula keimikala lawelawe i nā mea maʻi me ka umauma Ka maʻi 'aʻai, a me metastatic ke kahua. Ma keia hihia, no ka mea hoʻohana i loko o ka? Aieao wale, a hui lapaʻau me contraindications a me ka nele o ka hopenaʻoi loa o ka chemotherapy. Loa pinepine, hui capecitabine me ka docetaxel.

Ua ua i hoakaka i nā mea maʻi me ka maʻi 'aʻai o ka AeXIeAaOIePEAaI, esophagus, opu, pancreas, colorectal Ka maʻi' aʻai, nā ma ka kūloko hohola ana o ke kahua, a me i metastasis. Ma ka iapaau ana o ka AeXIeAaOIePEAaI Ka maʻi 'aʻai ua hoi ia "capecitabine". Na Ke Kumu no ka hoʻohana pono e hahai i ka paipai laʻau heluna, a hoopili aku i ka'ōlelo aʻo o ka hele kauka.

AaOIeIOUIeXAOAaIN me nā ai '

Inā chemotherapy hoao ineffective, he oncology hoʻomalu e koi 'ia i ka hui pu ana, lapaʻau, a e e hoʻohana "capecitabine". Na Ke Kumu no ka hoʻohana hoʻolako i ka papa inoa o nā kumu waiwai, i mea hiki e ana hui.

No ka laʻana, a me "docetaxel" - lāʻau cytotoxic hana a type me kaʻai kumu. He hiki ke hoomau anei oukou no ka manawa lōʻihi ma ke keena ma ka kiʻekiʻe nā hoʻohui like. Eia naʻe, e like me ka hoʻohui pū 'ia o ka Luna ua contraindicated no kanaka me ka helu ana o platelets a neutrophils 100.000 / Ul a me 1500 / l, niioaaonoaaiii. No hoi "Docetaxel" aole i pili i nā mea maʻi me ka māhuahua uku o ka bilirubin. Ma keia hihia, ke hiki kaʻawaʻawa loa hopena. Inā "Docetaxel" no kekahi kumu "haule ana" o ka iapaau ana regimen, hoʻomau Inc "capecitabine", akā, ma ka ho'ēmi i kā nā māhele.

Ma ka hanana o ke hypersensitivity reactions lapaʻau "capecitabine" a me ka "docetaxel" holo ana, a hoʻopau i nā symptoms, kena ae la. Noaia alu supplementation e hoʻomōhala ana i oncologist akamai artisan. Kēia noaia ua like i loko o ka hanana oʻawahia loa.

"Capecitabine" ua i hoonohoia ma ka ia manawa "Sorivudinom" - he antiviral Agena. Keia hui malu pu ana ke hoʻonui aku i ka kaʻawahia o ka lāʻau mua. I ka hui 'ana o antiepileptic lāʻau "phenytoin" maoli i ka lehulehu o ka hope i loko o ke koko wai koko. Ua mea no hoi e hiki kahe ana ke koko kāna hana i loko o ka hoʻohana o coumarin anticoagulants a me ka mea, ma ka papa kuhikuhiE ke keʻena - capecitabine. Na Ke Kumu no ka i olelo aku o ka hiki hopena, pela no oe e familiarize mua oe ia oe iho me ia.

ʻO wai ka mea i contraindicated?

Ke kumu i ua contraindicated paha ua kaupalena 'ia ka lāʻau e e.

• High pā lonoaʻili (hypersensitivity naoh).
• Ke alo o ka loaʻaʻa puʻuwai a hepatic insufficiency.
• Ke Kula Kaiapuni 'kahua o ka hoʻonaʻauao o ka hāpai keiki (i ka lāʻau e loli ai i ka hua), a me ke koe o ka hihia ma ka makuwahine ka ola ua waiho i loko o makakoho;
• Hanai ana oia i keiki e ai ana.

No hoi e loaa ana capecitabine kali no ka poʻe me coronary naau maʻi (CHD), ka wā o ka noho ana o ka mahuahua lehulehu o bilirubin i loko o ke koko, ake maʻi metastatic i ka 'aʻe ana i kona walaʻauʻana i hana'. i ko lakou hoomakaukau ana ua pono no Minor, a me nā kūpuna. Kēia keʻae i ka lāʻau "Capecitabine" ke aʻoʻia. E hoike olelo e pili ana i keʻano o kaʻaoʻao 'ole a me kaʻawahia' ole i loko o ka iapaau ana. Nolaila, capecitabine Inc i wahi ma lalo o ka ikaika nā limahana o ka hoʻomalu oncologist.

He loaʻa i kekahiʻaoʻao ona?

Ma hope o ka lawe ana i ka lāʻau 'ke e ka headache, moku'āina o ka luhi, lethargy, nawaliwali. Kanikani'āʻula kānāwai, a me ka hope versa - drowsiness. Ma pohihihi keia hihia - poho o ka ōhumu a kaulike, hilahila.

ʻaoʻao 'ole ma luna o ka mea'ōnaehana mānowai koko'ōnaehana mea anaemia (anemia). I ka mea uuku loa ia i i angina, myocardial ischemia, hahauʻana, naʻau ole a me na mea e ae. Inā i ke kaʻina hana o ka ÷ naehana hanu nā loko ka pae'āina, ma laila e e pokole o ka hanu, eha puu, cough. Loa kākaʻikahi - pulmonary embolism, akemāmā spasms.

Wā hoʻohana 'ia i loko o ka haku mele wale a hui lapaʻau hiki hopena maikaʻi' ole ma o ka musculoskeletal nenoaiu. Ua hoike mai ai ia ia iho i loko o kaʻeha ma na lala a me ka pūhaka, e ala hypertonus nāʻiʻo (myalgia), amiʻeha (arthralgia).

Ka ili i ke aloha no hoi. Hiki i dermatitis, erythema, excessive dryness o kaʻili, redness, tingling, numbness, kaha onionio, ka ohane, mahuahua pigmentation, poho e loli ai kui. Ma pohihihi keia hihia, ua ili mawae, hypersensitivity e ultraviolet pāhawewe, kaha onionio a mahuahua fragility o ke kui papa.

Mawaena o adverse hanana'ē aʻe i hana infectious keʻano o ka hanaʻana aie i lalo loa i ke kino i ka pale aku ia lakou. Ma hope o ka lāʻau 'Inc ke kumu o ka emi ana i loko o ke koko platelets, a keʻokeʻo koko keena. Ia hoike ana wehewehe i ka medicament "Capecitabine" manual. Analogues haawi aku i ka ia ole.

i ka lāʻau

"Capecitabine" kupono wale no na hana. IeAUPIIe, IAa IO ka mea, ua holoi ia me ka wai ma hope o ka hapalua o ka hola ma hope o kaʻai, akā,ʻaʻole hope. Na kela la i keia mahele lāʻau me ka nānā 'ana i ka hele oncologist, ke kaumaha ma muli o ka nui o ka hikoko, ka hooulu ana ke kahua, a me ka huina o na kino' ilikai wahi. Ua mea kupono i ke hoʻomalu i mua i ke akamai pū nō hoʻi, e hana i keia k. Ka loa pinepine hoakaka palua-kela la i keia - kakahiaka a me ke ahiahi. Ma keia hihia, ke papa holoʻokoʻa mau mau pule, a laila, - i ka mokuāhana iʻehiku lā, i ukali ia e ka hou lapaau.

No nā mea maʻi me kaʻaʻa puʻuwai insufficiency, i ka i kela la nā māhele hoemiia. Ma ka hoemi i ka helu ana o leukocytes (leucopenia) a me neutrophils (neutropenia) i loko o ke koko hoʻomau lawe i ka waiʻona. No laila, ia kekahi i kekahi mea o ka "Capecitabine" manual. Synonyms paha analogues lawelawe ma ka Initiative o ka hele kauka.

kaʻawahia

He nui na degere, e like me a uluʻawahia 'ole o ka lāʻau "capecitabine" (Na Ke Kumu no ka ho ohana i). Reviews o na kanaka e olelo aku i keia mea he kanaka kaʻina.

He nui na degere o kaʻawahia.

• 1 loa. Aia i mauʻaoʻao ole.
• 2 degere. Ka mea, pili diarrhea (i ia 4 manawa i ka lā) hahai ma ka lala nani, redness, hana kāna hana, he nihinihi hoomahuahua i loko o bilirubin. Ma keia kahua, ke hiki aku? Uaaiey capecitabine a me na hoailona o kaʻawahia o ke kahua 1.
• 3 degere. Diarrhea e hoola ae mai i ka 9 manawa no ka lā. Ua lŘlŘ malabsorption (sprue). I ka wa i mālama i ka ikaika ili kaha onionio, redness, blisters a me na mai hehe keia. Aia, Ua lena eha ma kaʻaoʻao, ua hoʻemi hana ana. Bilirubin ua hoomahuahua ia ka 3 manawa. Ma keia kahua o ka lapaʻau ua hele aku, a me ka hoike ana o kaʻawahia o 1 ka papahelu hoʻomau loaa ana hoʻi i loko o ka lalo mahele lāʻau.
• 4 degere. More pinepine diarrhea - mai i 10 mau manawa no ka lā. Noho me ke koko. Aia He He pono no ka hoike o ka ai ', piliwaiwai i ka gastrointestinal'āpana. Inā na hoailona o keia degere o ka lapaʻau E e pani, a aole loa hou.

He aha ana Pono e mālama palekana?

I ka papa o ka lapaʻau e lawe wahi ma lalo kokoke loa 'inikua hooponopono. Ke hoʻomalu pono 'eleu huai aeʻawahia hoikeana -, Ina paha e makemake nausea, diarrhea, etc. Ma ka loaʻaʻana o kēia mau hiʻona, i ka iapaau ana ua like. Inā pono, hoʻopau symptoms, emi ka kela la i keia mahele lāʻau, e ka wanaao ae. Lapaʻau E e hoomau, ina na hoailona o kaʻawahia mai i oweliweli i ka hoʻoweliweli 'ana i ke ola.

No ka poʻe me coronary naau maʻi hoʻomakākiu hoʻomalu e e oi loa hoʻokolokolo pono. Ma keia hihia, e pono manawa, e hoike aku i ka hopena maikaʻi 'ole ma luna o ka mea'ōnaehana mānowai koko'ōnaehana, a ma ka manawa, e hana i ka mea hooponopono.

Poe akamai i mea iki aku oukou i ka hana o ka waiwai i loko o pediatric hana. I ka laulā o kona hoʻohana i ole, ua hoʻokumu 'ia no nā keiki. Inā lapaʻau ua hoolilo i ka wahine o ka hanau keiki ana kona mau makahiki, ua pono e ao aku ma ka hopena o ka capecitabine ma ka fetus. I loko o ka papa o ka Inc,ʻo ia e hoʻohana ike loea contraceptives.

Hoomakaukau, a analogues

Aia i kekahi mau huahana ma ke kulanui o capecitabine. Ma ka Lūkini kuai, he 7 kuai inoa o ka lāʻau, hua mai la ma kekahi mau wahi lulu, a na hui. No kekahi laʻana:

• "Capecitabine".
• "Capecitabine-aku".
• "Tutabin".
• "Xeloda".
• "Kabetsin".
• "Kapetsitover".
• "Kapametin FS".

Mai ka hookumuia'na mai o kēia mau mea a pau i kekahi, a me ka iaʻeleu 'Oponopono - capecitabine, no kā lākou aʻoʻana, e e like. IeAUPIIe, IAa IO ia Hōʻike i ka papaʻaina no ka helu ana i ka laʻau heluna haawi kino ke kaupaonaʻana, a me ka hana? Iaea huakai kaapuni ia i ka hoailona o ka loli iki ana degere o kaʻawahia.

He nui no ka maopopo i ka mea mua e e heluhelu, ua hoonohoia ka wā la ia, no ka laʻana, "Capecitabine aku" - ke aʻoʻia. Ka 'ike he ilaila mea e pono ai ka hoʻoponopono-hooponopono hana! All omaulia e pili pū ana i ka mahele lāʻau a me ka lapaʻau regimen, produces he kauka - oncologist me ka lawa mākaukau ma kēia mea. Pakiko-aaieieno? O anticancer konohiki ma o na la irreparable ino i ke kino.

E kekahi o na ai 'mākou noʻonoʻo.

Description o ka hoomakaukau

• "Capecitabine - aku" i ka Lūkini poe OOO "Technology o ka lāʻau." A ki ke keʻena - capecitabine. Na Ke Kumu no ka hoʻohana, i ke kalaʻana aku palapala o ka hoihoi ana i na mea he nui. E noonoo oe i ka details. Kēia papa, ho film-kapa komo iā ia. Ka maʻiʻo o kaʻeleu waiwai - 150 a me 500 mg. Kākoʻo eiiiiiaiou: kelulose, lactose, croscarmellose paʻakai, hypromellose, makanekiuma stearate. Kekahi AEeAaOA paha e 60 a 120 na papa, ke kaumaha ma muli o ka laʻau heluna o ka lāʻau "Capecitabine - aku". Na Ke Kumu Pono e komo piha 'ana i ka pono o ke dala.
• "Capecitabine" - wahi lulu huahana me ka ia hana 'Oponopono. Kona hōʻikeʻano mea like me ka mea i helu 'ia ma luna. Release ano o ka lāʻau "Capecitabine" - papa. i Na Ke Kumu no ka hana, ua puni i loko o ka AEeAaOA.
• "Kabetsin" - anticancer Agena o ka Lūkini hana ( "Company" Deco "). Product palapala - papa ho film kapa komo iā ia me ka 150 a me 500 mg oʻeleu waiwai. Secondary nā mea hoʻohui: microcrystalline kelulose, crospovidone, pia, makanekiuma stearate. E haʻalele mai keʻena kūʻai lāʻau lapaʻau wale nō e kuhikuhi.
• "Kapetsitover" - he huina hoonui o ka Lūkini poe OJSC "Veropharm". Kēia anticancer hope paha i loaʻa i loko o na papa o ka 150 a me 500 mg o 60 - 120 apana. Ma waho capecitabine, ma ka la hoomalolo kikowaena lactose, kelulose, croscarmellose paʻakai, paʻakai stearate, a me ka hypromellose.
• "Kapametin FS" - hua mai la ia e Lūkini poe "Nativ" - heʻeleu aku i komo i loko o ka polokalamu o ka hoouku hakahaka o ka ai '. "Kapametin FS" wehe i ka laʻau heluna o 150 - 500 mgʻeleu Agena - capecitabine. Na Ke Kumu no ka hoʻohana (i ka hoʻohua E hoʻopaʻa i loko o ia), e hai aku oe i ka nui o na papa io no pack - 60 paha 120.
• "Tutabin" - haole huahana ma ke kulanui o capecitabine. Ua produces he Argentine poe Laboratorio VARIFARMA SA, i mea i na Luna Agena. "Tutabin" ua hua mai i loko o ka palapala o ka papa me kaʻeleu 'Oponopono maʻiʻo o 500 mg. 'ōpala - pepa pahu me na ao hakahaka.
• "Xeloda" - he antitumor hope paha. Hua mai ma Kuikilana ma "ma F. Hoffman La Roche" a me kona nāʻaha hui iho a me ka 'elele oihana i loko o nā'āina - Mexico, a me kaʻAmelika Hui Pūʻia. Ma ka Lūkini kuai, he 5 ai 'me ka oihana inoa. Product palapala - papa (150 - 500 mg) ma 60 a me 120 mau apana. i loko o ka hookahi AEeAaOA.

Reviews

Reviews o ka hana ma luna o ka muli o keʻano o ka ai 'capecitabine. Ka hapa nui o ia e 'oluʻolu, akā, ma laila nō i io nāʻana. Naʻe, i kēia 'aʻole i emi iho i kēia mau dala e like me ka maikai paha, he ino paha, no ka mea, au e mau loa ko oukou lawe i loko no o ka individuality o ke kino o kēlā me kēia kanaka. E loaa ana i ka mea 'ano o kekahi mau kanaka, aole loa e haawi mai i ka ia hopena. O ka nui o ka mea i kino i ku neoplasm, a pehea lā ka lōʻihi o ka mea i hele ma.

People mea i ka lāʻau, wahi a ka ikaikaʻawahia ia ma hope o kekahi mau lā o ka komo. Eia naʻe, he nui hōʻikeʻiʻo hana i loko o lākou kulana a hiki komo i loko o ke kala. An nui ana i ka lāʻau ', e hana e like me e hiki no i ke kanaka hookahi, i ka ke kuka mau oncologist a me ka ikaika adherence i kona mau kauoha e pili ana i lapaau.