"Celecoxib": aʻo no ka hoʻohana, nāʻana. lāʻau analogues

Iapaau ana o ka mai pili me ka poho i ka musculoskeletal'ōnaehana, e koi mai ka mea lāʻau lapaʻau market, e kāinoa hou ai 'me ka poʻeʻuʻukuʻaoʻao ona, a nui ka hoʻokōʻana. ua 'ike akula' epekema a synthesized i ka hou hanauna o ka 'ole-steroidal Anati-hoʻoʻino ai' ma ke kulanui o celecoxib. ua hoemiia mau ai 'kaʻawahia, aʻoi aku ka maikaʻi tolerated ma ke kino.

Description o "Celecoxib" lāʻau

Waiwai celecoxib i ka haikea melemele ke kala, a pili ia i ka pae coxibs i ho'āʻo e wae inhibition o cyclooxygenase ka lua type. Medicaments ka nānā 'ana ma ka hui ana o ka makana noho haʻi Anati-hoʻoʻino a me ka analgesic waiwai. Ka mua lāʻau ma luna o ke kumu o ka celecoxib ua manaoia e e hoʻomohalaʻia e ka poʻe 'Amelika "Pfizer" lāʻau "Celebrex". ka mea, ua hoʻopaʻa 'ana a me ka hoʻokolokolo i ka pharmacodynamic ano o kaʻawahia i ke kanaka kino.

ʻO nā medicaments i loaʻa i ka hana waiwai celecoxib i nōhie, a me ka lāʻau ' "celecoxib".

laʻau heluna 'ano apau loa

Available lāʻau i loko o ka hana gelatin capsules ma ka laʻau heluna oʻeleu 'Oponopono, 100 mg a me 200 mg. Haʻalele nā 'ole-steroid Anati-hoʻoʻino hope,ʻaʻohe laʻau heluna ano me ka poni, tuko pīlali, injectable pāʻoihana a me ke kula. Me kekahi e hoomanawanui i kuhi hewa o ia hoʻokuʻu palapala "Celecoxib" lāʻau '- na papa, aole makou e kamailio e pili ana i na capsules.

'ole

Kaʻeleu 'Oponopono ka celecoxib waiwai i loko o ka nui o ka 100 mg a me 200 mg. I ka haku mele 'ana o nā capsules nā kākoʻo eiiiiiaiou mea i ka lewa iie, ka flowability a me kumupaʻa o ka granulated ukuhiia. O nā lactose, paʻakai lauryl sulufahate, polyvinylpyrrolidone (K30), paʻakai croscarmellose, makanekiuma stearate.

Pili ana i ka lāʻau "celecoxib" manual maupaʻa i ka haku mele 'ana a me ka ano helehelena o ka gelatin mea hōʻikeʻikeʻuʻuku iwi. E like me ka hōʻike, ka mea nana hoopaa hoi, i aneane keʻokeʻo ma ka waihoʻoluʻu a ua hoailono aku la ia me na hoailona, "100" a me "200", Aia ma luna o ka mea uliuli a melemele koa, niioaaonoaaiii. Ua apono 'e hoomaopopo capsules me kekahi mau dosages. Haku mele 'ana o ka melemele a me ka uliuli ka inika i kekahi pena au mamuli e hoike ana i make e noho malie hoi e meaola.

like ai '

Lāʻau lapaʻau huahana "Celecoxib", analogues o ka a i loaʻa kaʻeleu waiwai celecoxib, ke ho'āʻo i ka ia pākōlea hopena ma osteoarthritis o na kanaka iwi.

Ka palapala lāʻau "Celebrex" a me kona nōhie "Celecoxib", "Artoksib", "Zitsel", "Revmoksib", "Ranseleks" e manaoia interchangeable lāʻau. Naʻe, ka mea mua kumukuai waeʻano e loaʻa i ka mea o ka nui oi pipiʻi ma mua o kā lākou mau counterparts.

No ka hoʻomäkaukau ' "Celebrex" he celecoxib ma ka laʻau heluna o 100 a me 200 mg like me ka medicament "celecoxib". Kākoʻo eiiiiiaiou o ka mea hōʻikeʻikeʻuʻuku a me kona wahī e oko nā ma qualitative a me ka laupaʻi haku mele 'ana i aʻole e pili mai i ko lakou mau waiwai. E pili ana i ke ano o ke kala o nōhie "Celecoxib" lāʻau analogues i hua mai la wale i loko o ka hana gelatin capsules no na hana.

Aia i 'ole-steroidal Anati-hoʻoʻino konohiki, cyclooxygenase like pili ana i ka lua o ka type akā, ka oko ao ma o ka haku mele' ana o kaʻeleu ke keʻena, ai ka pharmacokinetic a me pharmacodynamic ano. O nā ka sulfonamide hui nimesulide i loko o ka kela la i keia laʻau heluna o 200 mg kuleʻa Hawaii na symptoms o osteoarthritis a me rheumatoid arthritis. Mea haʻilula keimikala ka nānā 'ana ma luna o kona Anati-hoʻoʻino a analgesic kanawai ma ka inhibiting ka cyclooxygenase lua, a me ka uuku loa - o ke' ano mua, he aha ka mea iʻano o ka 'uao i kaʻeha a me ka li nui.

Like nimesulide, celecoxib ka 'elele o ka sulfonamide papa o ka waiwai, a me ka hoi i loko o ka kela la i keia laʻau heluna o 200 mg eliminates symptoms o osteoarthritis. Ua 'aʻole i inhibit i ka cyclooxygenase muaʻano a me nāʻoihana'ē aʻe ma luna o ka uuku o ka' uao i kaʻeha a me ka li nui.

I kekahi koho lapaʻau coxibs ku una hooponopono i injectable ano o NSAIDs. Kekahi o na kumu pono o "Celecoxib" huahana - ke kumu kūʻai. Injections (ampoules no ka pahu kui) 'ē' ole-steroidal Anati-hoʻoʻino ai 'loaʻa hou pipiʻi, akā, e like me ka pahu kui ka hoʻokōʻana i mamao loa i oi i ka hopena, mai ka hana o ka ai' i loko o paa 'ano apau loa.

ʻano papa hana o ka hana

Uluwehi O "Celecoxib" - he lāʻau e ho he hou hanauna o nonsteroidal Anati-hoʻoʻino konohiki, Anati-hoʻoʻino, analgesic, antipyretic haʻawina. Konaʻano papa hana o ka 'ana ua pili me ka paleʻana i ke kahua o ka hoʻoʻino prostaglandins e hoemi i ka ha awina o Punk-2.

Hoʻoʻino reactions kāhea i ka hoʻokomo o cyclooxygenase lua type, ma ka huli hōʻeleu i ka hoʻomāhuahua o prostaglandin hoʻololi kemikala a me ka waiwai i ka hōʻoi 'li nui. State hoʻomōhala i ka nani a me kaʻeha.

Cyclooxygenase muaʻano aʻole e pili mai ka pākōlea mahele lāʻau "celecoxib" hoʻomākaukau. Na Ke Kumu no ka hoʻohana iienuaaaony i ka 'oni' ana o ka lāʻau me ka manao a hiki i keia'ūhū pili i kona hana o physiological keʻano o ka hanaʻana 'ia i loko o na keena o ka gastrointestinal'āpana a me ka platelet hale.

Nō hoʻi, ma ka olelo haawiiaʻikepili ma o ka hopena o ka ai 'ma luna o nā puʻupaʻa. Ma lalo o ka hana o ka celecoxib Ua emi ma mua e hōʻike 'ia ma ka mimi haku mele' ana prostaglandin E2 a me F1 o 6-keto-prostaglandin, akā, 'aʻole e hoʻololi i ka auaaeaiea o B2 11-dehydro-thromboxane, i Hōʻike ka e wae hopena ka lapaʻauʻia.

E ho ohana ana o ka lāʻau "Celecoxib" aole i alakai i ka emi ma ka kānana ana i loko o ka hakuʻala glomeruli kūpuna, a me nā mea maʻi me kaʻaʻa puʻuwai insufficiency.

Nāʻikepili no ka hoʻohana

E like me ka pharmacodynamic ano o ka la hoomalolo "celecoxib" noi ka mea, e ia mana no ka lapaau ana i rheumatoid a me ka psoriatic arthritis, maʻi li nui me kaʻeha o ka spine a me ka sacroiliac ami a me ka osteoarthritis.

Manawa i kona analgesic waiwai i hoʻohana no ka ola ana i loko o musculoskeletalʻeha ma hope o kaʻoki lāʻau lapaʻau lapaʻau, dysmenorrhea, i ua pu e ola menstruation. Ke Anati-hoʻoʻino hopena o ka lāʻau ua pahuna ma hoemi outgrowths a me polyps ma ka AeXIeAaOIePEAaI a me ka rectum i loko o kaʻike, o "adenomatous polyposis".

Pehea e lawe

E lapaau "Celecoxib" kauoha no ka hoʻohana 'o loko i ke heluhelu ole ai pili aku me ka hoopau ana o ka ai. Nā capsules mai e wehe a me ka ole mama, a moni a pau ma ka inu nui ana o ka wai.

ʻO kā mākou dala o ka celecoxib, i hiki ke laweʻia no ka lā, he 0,4 g. Ua makaukau ua hoʻohana 'ia ma ka oi wale me ka pohihihi keia hihia.

Mea'ōnaehana mānowai koko complications hiki i kiʻekiʻe nā māhele, a hooloihi ae i hana ia me ka lāʻau "Celecoxib". Alakaʻi kekahi mau 'ike ma luna o dosages uuku no ka symptomatic iapaau ana o kēlā me kēia heluheluʻana. I nā koi ma pōkole ana.

E hoʻopau i nā symptoms pili me ka osteoarthritis, a me ka ankylosing spondylitis, i kela la lawe i kekahi paha mau manawa me 200 mg o ka lāʻau.

E hoʻopau i nā symptoms o rheumatoid arthritis ka hoʻohana 'ana i kela la i keia mahele lāʻau o 200 a me 400 mg, a i lawe ia i nā manawaʻelua.

Pain a iniiaiie dysmenorrhea ua malamaia lakou nei, i ka lā mua i ke kiʻekiʻe mahele lāʻau o 400 mg, a me ka hiki? Eaia o ka hou 200 mg, no ka lā hoʻohana 200 mg 2 manawa i ka lā.

Ke kūpuna, a me nā mea maʻi ua mehana ka papahelu lawa ake a mehana e hoʻokanahaʻiʻaʻa puʻuwai insufficiency, ua lawe mai i recalculation o ka mahele lāʻau.

Low ke kaupaona (emi o 50 kg), i ka awelika oolea o ke akepaa 'ole -ʻikepili waeʻano no nā mea maʻi malamaia lakou nei, me ka haʻahaʻa nā māhele o ka hoakakaia ka lapaʻauʻia.

Nō kāu, no ka iapaau ana o ka hoʻoʻino keʻano o ka hanaʻana i loko o ami hoʻohana lapaʻau nenoai muli ma ka hoʻohana 'ana o kekahi mau ai' o ka likeʻole laʻau heluna pepa. Hui pu iho "celecoxib" mea hōʻikeʻikeʻuʻuku, mea poni, a me ka tuko pīlali-type lalana ana ia ia "Apizatrona" a me "finalgon. Topical hoʻohana ke kumu he pokole ia, no laila, ka mea i hoʻohana pu me ka ai 'no ka i loko o? Eaia.

Keia ua papa i ka hana o

'Aʻole i nā mea maʻi a pau a me nā maʻi a pau o na ami, e hiki ke lawe i ka lāʻau "Celecoxib". Na Ke Kumu no ka hoʻohana he i ka papa inoa o nā maʻi a me nā kumu i loko o a ka mea paahana e oi pilikia ma mua o ka pono. Mau nā:

• hives, asthma, allergic ana ma o ka hana o ka aspirin a me nā nonsteroidal Anati-hoʻoʻino ai ';
• ke ola ana pili me ka coronary artery holo alaʻokoʻa pakuiia auanei lakou ;
• exacerbation o peptic ulcer;
• opu a me ka intestinal kahe ana ke koko;
• li nui o ka mucosa i loko o ka naʻau liʻiliʻi;
• naau ole;
• ischemic maʻi o ka naau Muscle;
• lilo o kaʻike ākea arteries a cerebral ipu me kaʻole cerebral koko;
• hepatic nedostatochnosttyazheloy shape;
• loaʻaʻa puʻuwai ole;
• ka hanau keiki ana;
• breastfeeding i ke keiki;
• ma lalo o ka makahiki o ka umikumamawalu makahiki;
• hypersensitivity i excipients;
• mahuahua susceptibility i ka sulfonamide ke keʻena.

Me ka akahele ana o ka lāʻau "Celecoxib" E e kanaka me ka maʻi o ka gastrointestinal'āpana pili me ka peptic ulcer kahe ana ke koko i loko o ka hala, maʻiʻaʻai o ka mucous koʻohune o ka genus Helicobacter pylori.

wai ka mālama i loko o ka kino a me ka pahee nā'aʻaʻa edema, kāna hana o ke akepaʻa haumāna ke kahua, naau a me ka vascular maʻi, i loko o ke kino, ai ka mea ulu i loko o ka naʻokoko pae i loko o ke koko wai koko malama lipid pūnao, mimikō, kōpaʻa, somatic maʻi ma ka loa, aʻo ka mea no ka i kā mākou akahele ana o ka lāʻau "celecoxib" ma lalo o ka hooponopono ana o ke kauka.

ʻaoʻao waiwai

I loko nō o ka hoʻonaʻauao kū hoʻokahi, e piʻi like i loko o ka hoʻokumu o ka hou hanauna o coxibs, i kēia mau waiwai, a ai 'ka nānā' ana ma luna o ia mea,ʻaʻole devoid o kaʻaoʻao loa.

Hele pū ana i ka lāʻau "Celecoxib" aʻo no ka hoʻohana ', ahonui e hoike a me ka hoʻomalu - mau kumu no ka' ike e pili ana i ka hiki adverse ole i kānāwai i loko o ka nui nā loko.

Ke hiki hopena maikaʻi 'ole ma o ka digestive'ōnaehana wehewehe aku ma ka NSAID-gastropathy,ʻeha i loko o ka abdomen, nausea, ka luaʻi, heartburn, ke emi i ka pono no ka ai a me kaʻai ana diarrhea. Lōʻihi-makahiki hoʻohana o kiʻekiʻe nā māhele hiki i ulceration, a kahe ana ke koko i loko o ka mucousʻili lahilahi o ka opu a me ka naʻau liʻiliʻi, kahe ana ke koko nui aʻe ana, excessive ho'ā hope o ka transferase akepaʻa.

Ko mākou hopohopo kāna hana i hoikeia mai pīhoihoi, headache, pōniuniu, somnolence, Kanikani'āʻula, depressive Hawaii.

Ole ma ka mea'ōnaehana mānowai koko'ōnaehana ma muli o ka mahuahua puʻe i loko o ka arteries, a me ka tachycardia.

E hoomakaukau ai "celecoxib" ho'ēmi i kā ia'ku i infectious maʻi o ka naehana oihana, i hiki ke hoikeia ma ka hooulu ana o ka sinusitis, rhinitis, pharyngitis,ʻeha ma ka ihu a me ka puʻu, cough, dyspnea, bronchospasm.

Ka hopena ma luna o nā lāʻau makaukau no ke kumu i ka ho'ēmiʻana i loko o auditory pokole, a me ka helehelena o ka tinnitus.

Ma ka urinary'ōnaehana e loli ai lāʻau "Celecoxib" ai ia oe i loaaʻaʻa puʻuwai ole me ka ulu o ka edema maʻi pale.

Me ka pili ana i ke koko-ho okumu i nā loko, i ka lāʻau hiki i ka hoike ana o ka agranulocytosis, anaemia, leucopenia, thrombocytopenia.

Skin rashes kānāwai me ka helehelena o ka allergic pruritus, urticaria, photosensitivity, angioedema i loko o ka lehalehu t aina,ʻaoʻao, genitalia.

hiʻona? eaia

Uluwehi O "Celecoxib" hoʻomaopop 'ana i keakea pili me ka māhuahua pilikia o adverse' ole ma luna o ka mea'ōnaehana mānowai koko'ōnaehana alakai i ka thrombosis, infarction o myocardial nani loa ka Muscle a me ka hahau ana. Oi loa aku hoi i ke kamepiula, piʻi pū iloko maʻi hooponopono o ka lapaʻauʻia ma nā mea maʻi i loko ona, he mea'ōnaehana mānowai koko maʻi.

E emi i ka pilikia ana o ia mau complications i loko o nā mea maʻi e lawe i ka lāʻau "Celecoxib" i koi 'ia i ka haahaa mahele lāʻau ma ka hapanui pōkole wā o ka nohoʻana. Ke hoomanawanui E kūkākūkā me kou kauka i ka hiki hoailona o ka maʻi, a, e loaa ia aʻo ma ka wā e hoʻomaka ai pehea e pane.

hana i kekahi hui malu pu ana o acetylsalicylicʻakika i loko o ka palena haʻahaʻa nā māhele i ka lāʻau "celecoxib" No ka emi i ka mea'ōnaehana mānowai koko symptoms. Reviews o lapaau hōʻike i ka antiplatelet kanawai o ka aspirin i lahilahi i ke koko ka wā lawe coxibs, a e ole i na mea Anati-thrombotic waiwai. Nō kāu, ua hōʻike 'ia i loko oʻelemākule e hoʻomanawanui iki mai i kāna hana o ka musculoskeletal'ōnaehana a me ka mea'ōnaehana mānowai koko'ōnaehana ia i kekahi hui malu pu ana, gastrointestinal kaʻawahia ua hoomahuahua ia i hoʻokoe'-e wae ole-steroidal Anati-hoʻoʻino ai '. Akā, i ke ano o ka waiwai celecoxib me nā NSAIDs ua ole paipai.

No nā mea maʻi e loaa ana mai ka kiʻekiʻe ke koko, ka mea ana ka mālamaʻana o kēia aiao wā e loaa ana "Celecoxib" lāʻau.

Mau noonoo E e hāʻawiʻia no ka mālamaʻana i keʻano o ka meaola i loko o ka hui pu ana me ka anticoagulant (warfarin) a me ka antiplatelet waiwai (acetylsalicylicʻakika, clopidogrel) hoʻohana e wae nā mea kūpale (citalopram, sertraline), inhibiting serotonin reuptake nā mea kūpale o CYP2C9 isozyme, papa 'ano apau loa glucocorticosteroids.

Ka lāʻau "celecoxib" ka paipai 'ana i ka? Iecaianoaaiiie o prostaglandin waiwai, a retard i ka wai i loko o ke kino a me ka hoʻokō' ana i ka edema. Pakahi aku la ia manao i loko o ka iapaau ana o kēia mau ai 'Pono e e kanaka e hana eha iaʻi mai ka naʻau Muscle ka hoʻokō' ole a me ka kiʻekiʻe ke koko. Oe e hooki lawe "Celecoxib" lāʻau ina he mau hoailona o ka nani o nā'aʻaʻa.

Nā mea maʻi me ka hakuʻala kāna hana lapaʻau coxibs e e ukali e mau hooponopono o ko lākou mau kī nā hoailona.

I ka lawe ana i ka lāʻau dehydration mea hiki ma hope o ka rehydration papa rehydration wale.

i ka hooulu ana o infectious olelo? eaia "celecoxib" antipyretic lāʻau ma muli o ka hoʻokō 'hele aku ai i complication o ka lapaʻau' ana 'inideka, e like me ke kiekie ana wela.

I ka hana o ka lāʻau i i abnormalities i ake hana, o ka oi aku i loko o kanaka me ka mālama '-na kāna hana o ke akepaʻa. Loa symptoms pili me fulminant hepatitis, ake nekrozomtkaney. Oia rula ana koke, akā, wale ma hope o 30 lā ma hope o noi "celecoxib" hoʻomākaukau. A laila 'oe makemake e kanaka hoʻoponopono hana ma ka iapaau ana o ke akepaa i kēia hale, a ina o ka mea kaumaha make ai oe e koke ana i ka manawa.

Reviews no ka iapaau ana o "Celecoxib"

Nonsteroidal Anati-hoʻoʻino ai 'ua lawe wale ma kuhikuhi. I ka hopena o ka pono o ka "Celecoxib" lāʻau hōʻike manaʻo o kona hana e hui. Kekahi ka lapaʻauʻia kōkua e Makuakane me ka hoʻoʻino keʻano o ka hanaʻana i loko o na ami, no ka 'ē aʻe ka mea, mea ineffective a ke kumu me ka helu o adverse hanana.

E like me ka nui nā mea maʻi loiloi i ka lāʻau "Celecoxib"? Reviews hōʻike i ka helu o nā pilikia:ʻeha i loko o ka'ōpū, hakuʻala, menstrual kāna hana. Oia nā mea maʻi kauka hanaʻia ke kāpaeʻana o ka medicament a me ka waihona 'ano like lapaʻau.

Ma muli o ka manao o ka hoʻomanawanui iki mai i ka hopena o ka ai 'o ka wela ai ami, ka mea hiki ke manao ia ia mea mana i loko o ke kaua e kū'ē i arthritis. E hoʻopau i ka eha symptoms, haanou ana o nā'aʻaʻa ma ka hoʻohuli ai i nā wahi o ka maʻi maoli, nā mea maʻi i loko o ka Akuma ka, a me ka kupulau uku o ka lāʻau Inc "Celecoxib". Ua Ua hoʻohana 'ia ma ka' âlapa ma trauma a me ka ami.

No medicament hana ka pono ma ka hui pu ana, me ka lalana ana ia ia me ka hinu a me gels no topical palapala noi. Eia naʻe, e like me na koi i kakauiaʻi ma na olelo ao no ka hana i haawiia mai NSAID hoʻohana pōkole papa, i mea e pale aku stress ma nā puʻupaʻa, ake, naau a me ka'ōpū. I ole ia,ʻaʻole e loaʻa hoʻolako 'ole' ana ma o ka hana ana i kēia mau kino.