"Finoptinum": aʻo no ka hoʻohana 'ana, haku mele' ana, maoli counterparts

Mai ka naʻau a me ka vascular maʻi e loli ai na mea he nui kanaka. A, me ka makahiki, ka pilikia ana o ia maʻi Hawaii ua nui mahuahua. E emi i ka pilikia o ka mea keʻano o ka hanaʻana i loko o ke kino, kauka waiho aku i ka hoʻohana 'ana o kūikawā hana. Iwaena o lakou i pololei ai mahalo i kalipuna Kanal blockers. Ka mea, eia he heterogeneous pūʻulu o ka ai '. Lākouʻano papa hana o ka 'ana ua pili me ka hiki, e inhibit i ka anal o ke kalipuna Ion, mai ka extracellular makahiki i loko o na keena a me nā ipu koko o ka naau. Hoemi i ka lehulehu o kēia mau kumu, ke medicament ka lawe vasodilating hana.

Ka loa ka hoʻokō lāʻau a me na waiwai o "finoptinum". Na Ke Kumu no ka hoʻohana ana i ka haku mele, analogs, nāʻikepili no ka hoʻohana ana i ka lāʻau a me kona aoao mau waiwai i hoakakaia i hoakaka ia.

Palapala, haku mele 'ana

He aha shape Ua ano o ka lāʻau "finoptinum"? Na Ke Kumu ma ke noi mai nei i ka mea hiki ke kuai me ka ka pahu kui a me ka huaale.

E like me ka hana 'Oponopono o keia Agena hana verapamil hydrochloride. ¶ A i loko o ka hoʻomākaukau nā likeʻole kākoʻo pili 'o Randy (ke kaumaha ma muli o ka kala pepa).

Pharmacological 'ole

He aha nā hiʻona i hoʻomaopop 'ana i loko o ka lāʻau "finoptinum"? Na Ke Kumu no ka hoʻohana 'ana, hōʻike manaʻo koi ia mea he kalipuna Kanal blocker (e wae) mua papa. He He derivative difenilalkilamina a me ka hōʻike antianginal, antihypertensive a me antiarrhythmic hana.

Antianginal hopena o keia k ua pili i kona waiwai, e loli ai i ka myocardium a me kaʻike ākea hemodynamics. Ma nā hua'ōlelo, ka lāʻau ho'ēmi i kā ka leo o arteries. Eia hou, e ho'ēmi i kā transformatsiiyu ATP ikehu i ka na i loko o ka kiʻekiʻe-ikehu ka pili ma loko o mechanical e hana, a ho'ēmi i kā myocardial contractility.

Mākou E hoi e hoailona oukou i ka hana o keia k me ka nui loa ho'ēmi i kā myocardial O2 a mai i ka io chronotropic, inotropic a me vasodilatory 'ole.

waiwai o ka lāʻau

Manawa i kona haku mele 'ana, ka medicament "finoptinum", analogues o i i helu' ia ma lalo, suppresses ka automaticity o sinus wahi ho'ēmi i kā af-conduction a maoli he ka refractory wā.

E māhuahua hoʻomaha manawa diastolic ventricle (hema), keia k ho'ēmi i kā ka tonus myocardial pā, a laila mea i kākoʻo 'ana no ka hana maikaʻi obstructive hypertrophic cardiomyopathy.

Ua E hoi e kaulana i noonoo lapaau hōʻike Anati-arrhythmic waiwai me ka supraventricular arrhythmias.

Nā kinetics o ka lāʻau

E hoomakaukau ai "finoptinum" aʻo i ua ho'ākāka 'ia ma lalo, ua ke kemu, mai ka digestive'āpana (ka hola 90% o ka mahele lāʻau). Kona hui ana me ke kumuʻiʻo o 90%.

Ka lāʻau 'Ua metabolized i loko o ka hooholo ia (mua) ma ke akepaʻa. Kēia 'ano apau loa e like me ka derivative like norverapamil ia mea emi hypotensive haʻawina ma mua o unmodified verapamil.

Ka hapa-ola manawa o ka lāʻau ma luna o loaa ana o ka hookahi laʻau heluna o 3-8 hola. Ma ke ano o ka puana nā māhele o ka medicament, keia huahelu loli aʻe (5-12 hola).

Loko lāʻau ma ka naʻau liʻiliʻi a me nā puʻupaʻa.

hoike

Ma kekahi mau hihia, i koi 'ia ka lapaʻauʻia "finoptinum"? Na Ke Kumu no ka hoʻohana (papa, a injectable pāʻoihana i ka ia showy) hākālia nō i kēia mea paahana hiki ke hoʻohana 'ia no supraventricular tachycardia (me paroxysmal, maʻi pale Lown-Ganong-Levine a me WPW-maʻi pale), hahau ana (anakahi uila, eii? Ole vasoconstriction, i ka pilina paʻa vasospastic), sinus tachycardia, atrial kolili, atrial tachyarrhythmia, atrial arrhythmia, hypertensive ulia (no ka intravenous hooponopono), hypertension, nui hypertension ma ka liʻiliʻi hvs i ka holo, hypertrophic obstructive cardiomyopathy.

Contraindications

I ka wa ole e lawelawe "finoptinum"? Na Ke Kumu no ka hoʻohana (injections a me na papa i ka ia contraindications) Hōʻike i keia mea paahana ua pāpā no ka hoʻohana i ka loa hypotension, sinoatrial hoʻopilikia a me ka maʻi sinus maʻi pale (koe i loko o nā mea maʻi me ka pacemaker), af-blockade o ke kolu a me ka lua o ka-degere maʻi pale Launa -Ganonga-Levin a me ka WPW-maʻi pale ma ka hui pu ana, me ka atrial fibrillation a atrial koliliʻana, hāpai keiki, hypersensitivity e verapamil, breastfeeding (maʻi kanaka me ka pacemaker wale nō).

Uluwehi O "finoptinum": kauoha no ka hoʻohana

Ke laʻau heluna o ka lāʻau he pōpilikia kauka pākahi.

Kanaka makua nā mea maʻi papa ua lawelawe hōʻike waha 'ia ma ka loiloi mua mahele lāʻau o 40-80 mg ekolu mau manawa o ka lā. No ka laʻau heluna ano me ka hookahi malama aku hookuu laʻau heluna e mahuahua e, a me ke alapine (frequency) o ka hooponopono - lalo.

Kids elemakule 6-14 makahiki, keia ka lapaʻauʻia ua? Aeiiaiaoaony e lawe i ke dala o 80-360 mg no ka lā, a mai ka 6 makahiki - ma ka mahele lāʻau o 40-60 mg no ka lā. Ke alapine (frequency) o ka hooponopono ana o ka lāʻau mea eha manawa i ka lā.

Inā pono, i ka lāʻau ma ka nīnau hiki ke lawelawe intravenously (lohi). Pela ia mea e pono ke kanaka hoʻoponopono i ke ECG, ke koko, a me ka naau lākiō o ka hoʻomanawanui.

Disposable pāʻoihana laʻau heluna no kanaka makua kānaka, he 5,10 mg. Inā ka pākōlea ia mea ma kahi'ē, a laila, ma hope o 20 minuke o ka la hoomalolo hiki e hou-komo (ma ka ia mahele lāʻau).

A hookahi laʻau heluna injectable ano o ka lāʻau no nā keiki 6-14 makahiki o ka makahiki o 2.5-3.5 mg na keiki 1-5 makahiki - 2-3 mg, a no ke keiki i ka hoʻokahi makahiki - 0.75-2 mg.

Nā mea maʻi me ka loa ake kela la i keia mahele lāʻau e ole oi 120 mg.

ʻO kā mākou laʻau heluna o ku una hoomalolo no ka lā, he 480 mg.

ʻaoʻao waiwai

E hoomakaukau ai "finoptinum" hiki hoʻonāukiuki i nā kēiaʻaoʻao reactions:

• ke kaupaona waiwai, bradycardia, agranulocytosis, a worsening naau hoʻokō 'ole', hyperprolactinemia, tachycardia, transient lilo o ka hihiʻo,ʻike ākea edema;
• na hiohiona ka ho'ēmiʻana o ke koko,, gynecomastia, galactorrhea, arthritis, angina, arrhythmia, pulmonary edema, af-aeie o ke kolu o ka degere, asystole, thrombocytopenia asymptomatic,'opi;
• nausea, oolea i loko o nā lima a me wāwae, gingival hyperplasia, maʻule hou ihola nō, luhi, māhuahua ma ka ikaika loa ka makemake, ka iini, mahuahua ma ka ake transaminases;
• ili poʻe noʻonoʻoʻole, pōniuniu, constipation a diarrhea, headache, kaumaha, sedation, extrapyramidal kāna hana, luhi, flushing o kaʻili, sleepiness, exudative erythema multiforme, pruritus.

lāʻau hana kūleʻa

Ua mea hiki, e hui pu iho la me nā laau lapaau "finoptinum"? Na Ke Kumu ma ka noi hākālia nō ia o ka hoʻohui pū 'ia o kēia mau Luna a me antihypertensive ai' ae hoʻohuiʻana paha i kā lākou mau antihypertensive hopena.

Ma intravenous aaieieno? O verapamil i kanaka, ka poe i nei loaa i kekahi mahele lāʻau o ka Hoʻokolohua-blockers, aia no he pilikia kiʻekiʻe o ka hypotension (arterial) a me ka asystole.

I ka ke kākoʻo '-lawelawe "finoptinum" lāʻau me ka Hoʻokolohua-blockers, lapaau no inhalation anesthetic a antiarrhythmic ai' maoli i ka pilikia o ka ulu naau e loaa, bradycardia, loa hypotension a door-blockade.

Together me ke komo "Amiodarone" listen bradycardia, io inotropic hookoia, af-hihia a me ka conduction haunaele.

No ka mea, verapamil inhibits isozyme CYP3A4, komo i loko o ka pūnao o simvastatin, lovastatin a me ka atorvastatin i e kekahi AaOIeIOUIeXAOAaIN hoikeana i i ke kumu e ulu nā hoʻohui like o statins i loko o ke koko. hihia o ka rhabdomyolysis i kekahi.

antianginal waiwai "finoptinum" listen ka wā hui me nitrates.

Together me ke komo 'ana o acetylsalicylicʻakika ua mahuahua kahe ana ke koko manawa ma muli o ka mea hoʻonui antiplatelet hana.

Hiki au e lawe "Dizopiramid" pu me ka lāʻau "finoptinum"? Na Ke Kumu no ka hoʻohana mau moʻolelo i keia hui malu pu ana i alakai i ka loa a me ka hypotension'opi, oi loa aku hoi i kanaka me ka decompensated naʻau ole paha cardiomyopathy.

I ka hoʻohana 'ana i nā na papa a me ka pāʻoihana maoli kona lehulehu i loko o ke koko a me "imipramine", a ma ka pilikia o ka hua'ōlelo i makemake loli ma ECG. Ua E hoi e kaulana ia verapamil maoli ka bioavailability o "Imipramine", hoemi konaʻae.

Me ka hui malu pu ana o ka ai 'me "carbamazepine" hoʻokāʻoi' hana o ka hope, e like me ka pono me maoli i ka pilikia o kaʻaoʻao 'ole, mai ka CNS.

I ka Ia manawa e lawe i ka lāʻau a me "clonidine" loaʻa nā hihia o ka naau ole i kanaka me ka hypertension.

I ka hoʻohuiʻia ka medicament me ka likiuma kalepona hoikeana o ka lāʻau hana kūleʻa i unpredictable a me ka hui. Aia nā hihia o ka neurotoxicity, loa bradycardia, ka hōʻoi 'i ka hopena o ka likiuma a me ka ho'ēmiʻana o kona lehulehu i loko o ke koko.

Like "Rifampicin" hana ma luna o ka lāʻau "finoptinum"? Manual Hawaii i keia me ka hui pu induces ake nā'ūhū, piʻi aʻe i ka pūnao o verapamil. He ultimately hiki aku ai i ka ka ho'ēmiʻana i loko o lapaʻau hopenaʻoi loa o ka lāʻau ma lalo o noonoo.

kekahi koi

He aha oe e ike mua ka hoʻohana 'ana i ka lāʻau "finoptinum" (40 mg)? Alakaʻi ai ia mau moʻolelo i ka hoʻohana i kēia koʻi me ka mālama nui ka wā af-blockade o ke degere mua, loa aortic stenosis, bradycardia, myocardial infarction me ke alo o ka hema ventricular ole, congestive naau ka hoʻokō 'ole ka maʻi maoli, lōpū a mehana hypotension, hepatic aʻaʻa puʻuwai insufficiency. I pono keia ka lapaʻauʻia ua pono no ka mea kūpuna a me Nā hana.

I ka huʻi pono e lawe mai ma ka hoʻohui pū Inc o hypertension a me ka angina ma verapamil a me ka Hoʻokolohua-blockers. Akā, he mea pono e pale aku i ka intravenous hooponopono ana o ka hope.

I? Eaia o kēia 'o ia hoʻi ka hoʻomanawanui i hoʻomōhala i na kanaka reactions e like me drowsiness a pōniuniu, a e pili i kekahi kanaka i ka hana, e hana hoʻopōʻino hana.

Hāpai keiki, a lactation

Ina he mea hiki wā e hiki mai hou makuwahine hoakaka ia ka lāʻau "finoptinum"? Na Ke Kumu no ka hoʻohana i hāpai keiki mai ia i kēia 'o ia hoʻi ka adverse hopena ma fetal ulu. Ua hoi ae i loko o ka umauma o ka waiu. Nolaila, ma lalo o kēia mau rula o ka lāʻau ua pololei contraindicated.

Medicament "finoptinum": counterparts a me ka waiwai e lilo aku

Ke kumukuai o keia mea paahana i e okoa. E like me ka rula, e hilinaʻi nui ma luna o ke kino o ke kala o ka lāʻau, ka mea a me ka laulā. Ka awelike kāki "finoptinum" He 100-170 rubles.

Inā noʻonoʻo i ka lāʻau 'oe e contraindicated, ka mea hiki auou caiaiai ia e kekahi o na kēia mau mea: "Verapamil", "Verogalid" "Verapamil-OBL", "Kaveri", "Verapamil Sopharma", "Verapamil-Lect," "Verapamil-Verein" "verapamil-ratiopharm" "Isoptin", "verapamil-Escom," "Vero verapamil," "verapamil hydrochloride" "Lekoptin".

Reviews o kauka a me nā mea kūʻai mai

Kilo'ōlelo aku nei au i na papa a me ka pāʻoihana "finoptinum" mea he pono a me ka inexpensive mea, a i ke hoʻololi i ka hoʻihoʻi hou ke koko, a me ka hoʻoikaika 'ana i pono-i i loko o nā maʻi' ē aʻe o ka ipu naau a me ke koko.

Like no me ka hoʻomanawanuiʻana, ka hapanui o ia mau loa māʻona i ka hopena o ka iapaau ana me keia Agena. Akala a intravenous infusion pāʻoihana kōkua ai i nā kokololio hoʻopau o symptoms o hypertension a me na hana mana e o ka pau ana o ka mea'ōnaehana mānowai koko nenoaiu.

Mākou E hoi e hoailona oukou ia e pili ana i ka lāʻau, a ike io ai ia mau moʻolelo. Ka mea, e'ōlelo aku o ka helu nui o kaʻaoʻao reactions e hana koke ma hope o ka hoʻohana 'ana i ka lāʻau. No hoi, he nui na mea hoʻohana ohumu e pili ana i na contraindications lehulehu.