He aha ka Addison ka maʻi?

Addison ka maʻi ia lŘlŘ ka wā o ka malfunction o ka adrenal cortex. Kēia maʻi ua diagnosed i loko o nā kānaka a me nā wāhine, ka hapanui waena-elemakule (30 a hiki i 40 makahiki). He mea pohihihi keia maʻi, a ua kakau i kekahi kanaka no 100 tausani. Heluna. Addison Biermer maʻi e hoʻomōhala ma muli o ke autoimmune keʻano o ka hanaʻana, infectious maʻi (syphilis, tuberculosis a me typhoid adrenals), a ma ka amyloidosis a me malignant hikoko. I ka 70% o nā mea maʻi, i ka maʻi ia lŘlŘ like me ka hopena o ka hoʻolako 'ole i loko o ka'ōnaehana paleʻea'ōnaehana (nā mea'aʻaʻa e hoomaka ana e lawe i ke kino keena no na kino, e hoomaau a me ka luku ia). Me ka make ana o ka adrenal cortex keena emi hoʻololi kemikala gluco a me mineralocorticoids (cortisol, 11-deoxycorticosterone, aldosterone). ʻepekema, ua hoike ia glucocorticoids hooponopono i like biochemical keʻano o ka hanaʻana i loko o ke kino (regulates ke koko, insulina lehulehu, ua komo i loko o ka rula o ka kumuʻiʻo hoʻololi kemikala, lipids a me carbohydrates).

Gipokortitsizm pinepine mālama i loko o nā mea maʻi ia me na hormones o ka adrenal cortex. Ma ka hapanui o na hihia, ka etiology o ka maʻi nō koe IKE OLE IA. Adrenal insufficiency hoʻolaha i loko o iniiaiie a me nā haumāna. Helu ole e hoʻomōhala ana i loko o ke pio ana o adrenal'aʻaʻa, a me ke kiʻekiʻe - ma muli o ka lawa ole stimulation o adrenocorticotropic hōmona.

Addison ka maʻi Symptoms

Lapaʻau na hoailona o ka maʻi, kena ae la ia e deficiency i loko o ka meaola mea pōhaku a me glucocorticoids. Ka loa ano hiʻona i nawaliwali, hypotension, dysfunctional gastrointestinal (nausea, lilo o ka ikaika loa ka makemake, ka luaʻi, constipation, diarrhea a pinepine auou caiaiai). Kekahi hoʻomanawanui iki mai hypochlorhydria.

Addison ka maʻi ua pu e mahuahua irritability a mau naau naʻau i loko, pinepine headaches a me Kanikani'āʻula. X-Ray o ka pahu hōʻike he emi i loko o ka naʻau o ka nui. Ke electrocardiogram mooolelo i ka hoailona o ka hyperkalemia (kiʻekiʻe potasiuma lehulehu i loko o ke koko). Skin pigmentation Aʻole e noonoo i ke oolea o ka maʻi, nae, ka mea ulu paha emi ia i loko o ka iapaau ana o ka hoike ma ka laulā o ka pākōlea hana.

Addison ka maʻi ua wehewehe aku ma ke kumu o ka mea kiʻekiʻe symptoms emi loa. Loa kākaʻikahi ka maʻi hoike mai ai ia ia iho, me ka pigmentation (no laila, i ka inoa o "keʻokeʻo Addison"). I ka papa kuhikuhiE kumu o keia maʻi ka tuberculosis adrenals. I ka wa e kaawale aku o kūpono lapaʻau Addison ka maʻi huikau. Lapaʻau hoailona i listen: nausea, ka luaʻi, diarrhea, ke koko, kulu ikaika, mahuahua i ka lehulehu o ka potasiuma i loko o ke koko. Ma kaʻike ākea koko o koena naikokene maoli i ka helu o kaʻulaʻula koko keena, hemoglobin. No ia mea, ina i ka wā o ka hoʻoponopono ulia addisonicheskogo hoomanawanui, aole ia i hoʻolako 'eleu kōkua, oia make ia me na hoailona o kaʻaʻa puʻuwai a me ka mea'ōnaehana mānowai koko maʻi.

Ka mea nui wale keʻena hoʻokolohua kiko'î a no kaʻike,ʻo ia ka maʻiʻo o 17-OCS i ka wai koko a me ka 17-KS i loko o ka mimi, me pono me ka emi i loko o ke koko monakō koko pae. Morphological ninaninau ana i ke koko Hōʻike lymphocytosis, eosinophilia a me ka ESR hoolohi.

Addison ka maʻi ua differentiated mai ke kēia mau maʻi: keleawe mimikō, pellagra, kaʻapu kōheoheo arsenite a me Bismut Argentum. Ka maʻi ana i kekahi maʻi papa me ka papa'āweʻaweʻa kemika ihu lua. Addison Biermer maʻi oolea manao ma ka oolea o ka nui na hoailona o ka maʻi, e like me ia ma ka helu o ka ai 'i mea e pono ai, e compensate no adrenal insufficiency.