Prokinetics - He aha ka mea? he hou ka hanauna o prokinetics: papa

Prokinetics - He aha ka mea? Ma ka Moscow'āina,ʻaʻohe mea i kona manaʻo ma e pili ana i ka lapaʻauʻia i komo i loko o kēia pae, no laila,ʻo kēlā kanaka gastroenterologist iho hoʻoholo i ka hana i kēia papa inoa a me ka mea mea ole. Prokinetics - He aha ka mea? O ia ka leo mea mākou ho'āʻo e loaʻa mai.

Definition a he manawa pōkole hōʻikeʻano

Prokinetics - He aha ka mea? Kēia pūʻulu o ka ai 'i hoʻoulu i ka motility o ka digestive Tube, a ua ālai' anastaltic ale.

pinepine Gastrointestinal maʻi pū 'oe me reflux o ke chyme mai na nā wahi haʻahaʻa o ka intestinal Tube ma ka overlying, kue hooholo ia bolus paha he stagnation i loko o ka naʻau liʻiliʻi Hoʻohana. A pau o kēia mau symptoms i pili me ka hihia hoʻi paipai 'chyme ma ka digestive Tube, alaila, e lawe aku oe i ka symptoms hiki ia, me ka hoohuoi ana i ka contraction o ka pahee nāʻiʻo i loko o kona pā pōhaku. Ia ka leo o ka prokinetics. Lākou pākōlea ia mea no i ka paleʻana o ka ion hooliloʻano papa hana (dopamine, 5-HT4 receptors, hoʻohui pūʻia) ai ole ma ka pūnao o acetylcholine. Loaʻa lapaʻau ia mea ku pono ana i ka mahuahua nui o ka acetylcholine i loko o ka mauae synaptic a me ka amplification o cholinesterase huahana i hoʻokāʻoi aʻe ana i ka decomposition o ACh, ka ho'ēmiʻana me nā huahana ACh nā aʻalolo a hāʻule pahū wale.

Physiologically 'ole mai i ka ai' ikea e hoomahuahua i cardiac esophageal sphincter leo, ke piʻoloke o ka opu Contents, ka ōhumu ma waena o ka antrum a me ka duodenum, hoʻomāhuahua ai liʻiliʻi peristalsis.

Ka mua pūʻulu o ka ai '

Prokinetics - ai 'i kal dopamine D2-receptors, ma ia noho haumāna kahi Muscle hope a me ka hoʻolako' gastrointestinal olona, antiemetic hopena. Mau laau lapaau nā: "metoclopramide" (mua hanauna laʻelaʻe 'ia - "Reglan" a me ka "Raglan"), "bromopride", "Domperidone" (lua o ka hanauna), "Dimetpramid", "Itopride".

Prokinetic ai ', hoʻohana' ia i loko o ka iapaau ana o ka gastroezofagialnoreflyuksnoy maʻi (GERD), YAZHDPK, dyspepsia, ooieoeiiaeuiiai ano, hou o ka esophagus ma hope ino, a me ka hopena o adhesions, postoperative paresis piʻiʻana i loko o ka abdomen, mai ka pioloke o ka outflow o bile, flatulence.

No hoi prokinetics - ai 'ana e hoʻohana hiki no nausea a me ka luaʻi, kena ae la ia e kaʻapu kōheoheo a' aʻe 'ana o na rula palaoa, maʻi o ka mea hoʻomaʻi a mea koʻohune etiology, hāpai keiki i loko o ka trimester mua, huʻi coronary insufficiency, poo trauma, anesthesia, pāhawewe a me ka chemotherapy. Ineffective ma ka luaʻi vestibular ka molekumu o, e like me ka mea aole i pili i ka waena pepeiao, a me ka medulla oblongata.

Antipsychotics kōkua me ka luaʻi

"Sulpiride" a me ka "Levosulpirid", mea he neuroleptic me ka likeʻano papa hana o ka hana, ka mea no hoi i ka maikaʻi Anati-emetic hookoia, no laila, hiki ke hoʻohana 'ia i loko o gastroenterological hana.

"Metoclopramide" (prokinetics): kauoha no ka hoʻohana

"Metoclopramide" - he pololei stimulator o malimali Muscle, a ua pau i ka mea waiwai, e hoʻokō clinically nui hualoaʻa, akā, no ka mea, o ka mea permeability gematogistologicheskie nā pale kaʻa e e hoʻohana me ka mālama nui. Hikiʻaoʻao waiwai e like me spasm o ka lehalehu t nāʻiʻo, i ka symptom o "ka moa mau wawae", rhythmic protrusion o ke elelo, bulbar kāna hana, spasms ekrtraokulyarnyh nāʻiʻo, spasmodic torticollis, excessive leo o ka extensor nāʻiʻo, Parkinson ka maʻi pale, somnolence, nawaliwali, tinnitus, headaches, ka iini, hilahila.

I kekahi manawa, pono e lawe prokinetiki? Na Ke Kumu no ka hoʻohana ana i olelo mai undesirable pono ma ka manawa o ka hypersensitivity i ka lāʻau, heʻeho no ka adrenal cortex, intestinal iaʻi, perforation o ka na naau oʻu me ka i mai ia lakou kahe ana ke koko, prolaktinozavisimoy hikoko, epilepsy a me extrapyramidal kāna hana, mai ke 16 pule o gestation ke keiki ka, i lactation, na keiki ma lalo o 5 makahiki. Kaiapuni E e hoakaka ia ma ka ho'ēmi i kāʻae o ka creatinine, mahuahua ke koko, asthma, kahiko mai i ka 14 makahiki.

Ale i ka lapaau hapalua o ka hora mua o ka mōhai, ma luna o ka papa ma 9:00, 12:00, 15:00 a me 18:00. Duration o ka lapaʻau - eha i eono pule, i kekahi manawa, ka mea hiki ke hāʻawi mai i ka eono mahina.

Inā ke kala palapala - wai, ka mea, ua lawelawe intramuscularly paha intravenously. No nā mākua a me nā keiki no 14 makahiki - 10 mg. I kā mākou no kekahi manawa - 20 mg kela la i keia mahele lāʻau - 60 mg. Kahi o ka ampoule hiki ke nāu kekahi ma isotonic Saline a 5% monakō koko pāʻoihana.

"Domperidone": kauoha no ka hoʻohana

"Domperidone" Ua oi e wae dopamine mea loaʻa blocker, he okoa i komo iloko o ka BBB, nae, i ka wa o ka? Eaia mea e hoʻomōhalaʻaoʻao loa i wehewehe 'ia ma luna. Naʻe, mahuahua ka secretion o prolactin, e triggers gynecomastia, galactorrhea, a me ka wa e kaawale aku o menses. Eia hou, e hoomanawanui i hai mai la i ka ili poʻe noʻonoʻoʻole, maloo waha, diarrhea a me headaches.

'Aʻole i haawiia no ka hoʻohana no ka poʻe me allergic reactions i eiiiiiaiou o ka lapaʻauʻia, kahe ana ke koko mai ka gastrointestinal'āpana, intestinal iaʻi, prolactinoma, lactation, makahiki a hiki i 5 makahiki o ka makahiki paha he mai i ka 20 kilograms. Kaiapuni, e lawe i hāpai keiki,ʻaʻa puʻuwai a me / ai hepatic insufficiency.

Inu no ka iwakālua minuke mua kēlā me kēiaʻai i 10 mg, ina pono, a me ka hiki ke inu mua ka hele ana i kahi moe. ʻO kā mākou mahele lāʻau no lā - 80 mg. Inā e noho i loko o ka iapaau ana o antacids, hoemi i ka secretion o gastric wai, ka mea e e kaawale mai ka inu domperidone, kaʻana like ai anaʻai.

"Itopride": kauoha no ka hoʻohana

"Itopride" hiehie ka waiwai o ka dopamine mea loaʻa hoa a me blocker o acetylcholinesterase. Ai ma luna o ka hypothalamic-pituitary-adrenal'ōnaehana, mahuahua nā hoʻohui like o ka somatostatin a me ka hoemi adrenocorticotropic hōmona. A hopena maikaʻi hookoia ua olelo ia me leukopenia, thrombocytopenia, hypersensitivity reactions, hyperprolactinemia, nausea, tremor, jaundice. Iloko o ke? Eaia, ia mea pono ke kanaka hoʻoponopono i ka moku'āina o kaʻike ākea koko, a ua hōʻoia 'loaʻa nō oleʻaoʻao ole.

'Aʻole i haawiia no ka poʻe me hypersensitivity o ke' ano koke a hoopanee, gastrointestinal kahe ana ke koko mōʻaukala, obturating ka intestinal lumen a mīkini'opihia o kekahi haole kino mai ole, ma lalo o ka makahiki o heʻumikumamāono makahiki, hāpai keiki, breastfeeding.

Ka lāʻau 'Ua lawe hōʻike waha' muaʻai no ka 50 mg ekolu mau manawa o ka lā.

Hakaka "Acetylcholine"

Kēia pūʻulu nā:

• "Aceclidine" (M-cholinomimetic);
• "Fiziostigmin" "Galantamine" "Tegaserod" "Prucalopride" (reversible cholinesterase inhibitor)

Mau ai 'no i wale hapa' ia 'poe o prokinetics no o ko lākou mauʻaoʻao ole:' ole ma o ka wehe ana o potasiuma Ion, a me ka hopena, hooloihiia mai QT wā mawaena, i hiki aku ai i ka haunaele o cardiac pāpana. A helu o ka ai 'i, ua haalele iho mai ka pharmacological kuai no keia kumu.

"Aceclidine": kauoha no ka hoʻohana

Prokinetics - He aha ka mea, pehea a me ka wā e hana mai ia lakou? Ma kekahi hihia, eʻoiaʻiʻo, e nīnau aku i ke kauka a me ka hooikaika ka study o na olelo ao no ka hana.

"Aceclidine" ua hoʻohana 'ia e pale emi o ka leo o ka digestive'āpana a me ka bladder ma hope oʻoki kino, ho'ēmi i kā intraocular puʻe, hiki no ia mea, e ia i loko o ophthalmology. Product palapala - ka pahu kui, injected subcutaneously me 2.1 ml o ka 0.2% pāʻoihana. Max i ka manawa - 0.004 g., A me kela la i keia ole hou aku 0.012, ma kaʻaoʻao ole - ptyalism, sweating, a me ka diarrhea.

Contraindications i ka hoʻohana 'i CHD, ke kiekie HDL, bronchial asthma, a me nā hyperkinesias parkinsonism, hāpai keiki, kahe ana ke koko mai ka abdominal lua.

"Fiziostigmin" ua hoʻohana 'kuhikuhi ma ophthalmic hana, akā, hiki i kekahi manawa hana ma gastroenterology ma ka intestinal paresis. Ka lāʻau 'injected ma lalo o kaʻili o ka 0.5 - 1 ml o ka 0,1% pāʻoihana. ʻO kā mākou dala o ka lāʻau no ka lā e ole oi 0,001 g.

ʻaoʻao 'ole nō ka hoʻoikaika' ana i ka salivation, bronchospasm, intestinal spasm o na nāʻiʻo, hou i loko o ka naʻau ana, convulsions.

Contra-nāʻikepili: angina, epilepsy, asthma, ma paʻi intestinal iaʻi, peritonitis, sepsis, hāpai keiki.

"Galantamine": kauoha no ka hoʻohana

"Galantamine" ma ka pau hihia ua hoʻohana 'ia e like me ka hoa no ka Muscle relaxants i loko o ka postoperative wā me ka emi ma Muscle leo o ka na naau oʻu me ka bladder. Contraindications i ka hoʻohana 'i hypersensitivity, epilepsy, asthma, ke koko ma luna o 139/99 mmHg, COPD, me mechanical occlusion o ka intestinal leki uea,ʻaʻa puʻuwai papa hoʻopilikia, makahiki 9 makahiki. Kaupalena ai i ka manao o ka hāpai keiki i loko o na ma ka Loaʻaʻia ia i hoeha mai ma mua o ka pomaikai. Ma lactation, hiki ke pū i hiki ai i ka bebe ma ka waiū.

ʻaoʻao ole: ka ho'ēmiʻana o ka naʻau ana, TTP, af blockade, arrythmia, nausea, ka luaʻi, diarrhea, dyspepsia, Muscle spasms, urinary incontinence, haematuria, tremor.

Ua hiki e lawelawe subcutaneously, intramuscularly, intravenously, transdermally, hōʻike waha. Ka mahele lāʻau Ua like pākahi, ma muli o ka mōʻaukala o ka maʻi, a e e? Ee e ka hele kauka. Ka awelika kela la i keia mahele lāʻau no nā mākua - mai ka 10 a hiki i 40 mg, i puunaue ai i mau a hiki i eha nā māhele.

A hou hanauna o prokinetics

Ma ke kumu o keia la Itopride paka ai 'e like me "Ganaton", "Itomed", "Pramer". Kekahi o ka Hou Loa a loa ka hoʻokō i ka poe prokinetiki hou hanauna e like me "koordinaks" a me ka "Prepulsid". ʻOiai ka mea, hiki i hoʻoponoponoʻaoʻao 'ole i loko o ka naʻau.

Ka loa kaulana i waena o gastroenterologists koe "Motilium" (ʻeleu 'Oponopono - domperidone), a hiehie i ka mea e like ai o ka metoclopramide, akā,' aʻole i i kona io hopena.

He aha nō ka loa ka hoʻokō pprokinetiki? Papa Inoa o nā huahana manawa mai nā ':

1. "Itopride" (ʻeleu 'Oponopono) - "Ganaton", "Itomed", "Primer" (kālepa inoa).
2. "Metoclopramide" - "Raglan" "Reglan".
3. "Cisapride" - "koordinaks", "Prepulsid".
4. "Domperidone" - "Motilium", "Motilak", "Motinorm", "Passazhiks".

Mākou e ike ana ia i ka prokinetic. Papa inoa ia e like me kou ike, ka mea, ua nui loa. Akā, e hoomanao, ma mua ka hoʻohana 'ana i kekahi ka lapaʻauʻia e kukakuka pu me kou kauka! E hoʻokaʻaʻike ola!