Hoʻokolohua-blockers: ai 'papa inoa, nāʻikepili no ka hoʻohana

Ai 'me ka nui pākōlea' ole i hoʻomano hoʻohanaʻia e hoʻomalu. Ka mea, i hoʻohana 'ia no ka iapaau ana o cardiac maʻi, a nō ka loa pinepine i waena o nā pathologies. Mau maʻi i oi paha, e alakai i ka make ana o nā mea maʻi. Lapaau i ka poe i pono, e hana i kēia mau maʻi, i Hoʻokolohua-blockers. List papa o ka ai ', oia hoi o ka 4 pauku, a me kā lākou Mea Maluna e hōʻike mai iā ia ma lalo nei.

Mea Maluna o ka Hoʻokolohua-blockers

Ke Nine Inch kanu'ōiwi o ka lāʻau papa ole-ʻaʻahu, a mai ka lapaʻau 'ole i kuokoa. Nui hou nui ke kālā līkaia no kekahi i ka kekahi mea loaʻa a me ka Solomona no ia. Ke kiekie o ka specificity no ka Hoʻokolohua-1 receptors, ka poʻeʻuʻukuʻaoʻao hopena o ka ai '. Ma keia manao, o ka papa inoa o ka Hoʻokolohua-blocker ai 'imua like rationally.

Ka mua hanauna o nā huahana.

• ole-e wae Hoʻokolohua-mea loaʻa 1 a me ka 'ano 2, "Propranolol" a me ka "Sotalol", "timolol" a me ka "oxprenolol", "nadolol," "Penbutamol".

Ka lua o ka hanauna:

• e wae Hoʻokolohua mea loaʻa type 1, "bisoprolol" a me ka "Metoprolol", "acebutolol" a me ka "Atenolol", "Esmolol."

Ku akolu:

• E wae Hoʻokolohua 1 blockers me ka hou pharmacological waiwai: "Nebivolol" a me ka "Betaksalol", "talinolol" a me ka "celiprolol".
• Nelektivnye Hoʻokolohua-1 a me ka Hoʻokolohua-2 blockers me ka hou pharmacological waiwai: "Carvedilol" a me "carteolol," "Labetalol" a me ka "bucindolol".

Mau Hoʻokolohua-blockers (nānā i papa inoa o ka ai '. Ma luna,) i kekahi mau manawa, he i ka papa kuhikuhiE pūʻulu o ka ai' ana i ua hoʻohana a ua manawa hoʻohana no ka maʻi o ka ipu koko a me ka naau. He nui no ia, ka hapanui 'elele o ka hanauna lua a me ke kolu, e hoʻohana i kēia lā. Ma muli o ia kā lākou pharmacological 'ole mālama i ka pāʻana naau i kela a paa ectopic pāpana i na ventricles, e emi i ke alapine (frequency) o ke angina ho'āhewa wale o ka angina.

Key i ka Mea Maluna

Ka mua ai 'mau lala o ka hanauna mua,ʻo ia hoʻi,' ole-e wae Hoʻokolohua-blockers. A papa inoa o ka ai 'a me ka hoʻomākaukau pono i haawiia mai ma luna. Mau ai 'hiki o ka paleʻana i nā receptors o ka 1st a me ka 2nd type, ka hoʻolako' nā pākōlea 'ole a me nāʻaoʻao, a ua kaheaia bronchospasm. No ka mea, ka mea e contraindicated i loko o nā mea maʻi me ka COPD, bronchial asthma. Ka nui o ka mua o ka hanauna ai 'i "Propranolol", "Sotalol", "timolol".

Mawaena o ka poeikohoia o ka lua o ka hanauna o ka papa inoa o ka ai 'Hoʻokolohua-blockers, i keʻano papa hana o ka hana ana i ua pili me ka, iniiaiie ka paleʻana i ka mua type receptors. Ka mea, i wehewehe aku e ka nawaliwaliʻo Solomona i ka mea loaʻaʻano 2, no ka mea, kākaʻikahi i bronchospasm i loko o nā mea maʻi me ka asthma a me ka COPD. Ka loa nui hoomakaukau o ka 2nd hanauna i "bisoprolol" a me ka "Metoprolol", "Atenolol".

Ke kolu o ka hanauna o ka Hoʻokolohua-blockers

Me ka Poeikohoia o ke kolu o ka hanauna - o ka hope Hoʻokolohua blockers. Ka papa inoa o ka ai 'nā "Nebivolol", "carvedilol", "Labetalol", "bucindolol", "celiprolol" a me kekahi poe e ae (e nānā, luna). Ka mea nui, mai ka lapaʻau wahi o Hawaii i ke kēia: "Nebivolol" a me ka "Carvedilol". Me Kinohi advantageously wahi Hoʻokolohua-1 receptors a stimulates ke kala o NO. Keia ua kena ae la ma ke anoe ana o na moku koko, a emi i ka pilikia o atherosclerotic plaques.

Ua Ua manaoio ia Hoʻokolohua-blockers - ai 'no ka hypertension a me ka naau maʻi, oiai "Nebivolol" - he nōhie lāʻau i mea pono hoʻomākaukau no nā hana. Eia naʻe, kona kāki mea iki ma luna ma mua o ka kumukuai o na mea e ae. Similar i loko o ka waiwai akā kānaka hou pipiʻi, ka mea, o ka "Carvedilol". Ua hiehie i ka waiwai o ka Hoʻokolohua-1 a me Alpha-blocker e kōkua e emi i ke alapine (frequency) a me ka mana o ka naʻau contractions, e like me ke hoʻonui i ka periphery o nā ipu.

Mau waiwai ae oe i ka mana maʻi naʻau ole a me ka hypertension. A i loko o ka hihia o ka naau e hemahema, "Carvedilol" - i ka lāʻau o ka poʻe uʻi a, no ka mea, no ka mea, he antioxidant. No ka mea paahana ua ālai 'aggravation o atherosclerotic plaques.

Nāʻikepili lāʻau pūʻulu

All nāʻikepili no ka pono o ka Hoʻokolohua-blockers hilinaʻi ma ka ho'ākāka waiwai o ka mea mau lāʻau pae. I 'ole-e wae blockers nāʻikepili iʻololī, ka mea hoi e wae lua pele a me ka hiki ke hoopili ma nā kaiāulu. I mau, na nāʻikepili i ole, aole ka mea, e kaupalenaʻia ka impossibility o ka pono o ka ai 'i loko o kekahi mau hoʻomanawanui iki mai. No ka 'ole-e wae ai' i kēia nāʻikepili:

• myocardial infarction i loko o nā manawa, angina, koena, ka poe angina ;
• Atrial fibrillation normoforma a me ka tahiforma;
• sinus tachyarrhythmia me ka lawe ana ia me me ia ventricles paha;
• naau 'ole (maʻi);
• hypertension ;
• hyperthyroidism, hyperthyroidism, me me ka ulia o ka mea paha;
• pheochromocytoma mai i ka ulia o ka walaʻauʻana Inc a maʻi preoperatively;
• migraine;
• Dissecting aortic aneurysm;
• lāʻau 'ino a withdrawal maʻi pale.

Aie i ka maluhia o na mea he nui nā pūʻulu o ai ', o ka oi aku ka lua a me ke kolu o hanauna, i ka papa inoa o ka ai' Hoʻokolohua-blockers, pinepineʻia i loko o ka mooolelo o ka iapaau ana o ka naau a me ka vascular maʻi. E like me ke alapine (frequency) o ke noi, ka mea, ua kokoke'ālike me ACE nā mea kūpale, a i hoʻohana ai no ka iapaau ana o ka naau a me ka hoʻokō 'ole' hypertension me metabolic maʻi pale , a me ka ia. Together me diuretics, kēia mau pūʻulu mau o ka ai 'hiki ke hoonui ola expectancy i ka maʻi cardiac ole.

Contraindications

Hoʻokolohua-blockers, e like me nā ai ', i kekahi contraindications. A no ka mea, ai 'hana ma luna o receptors, i lua pele ma mua o nā mea kūpale ACE mea. General contraindications:

• asthma, COPD;
• bradyarrhythmia, maʻi sinus maʻi pale;
• atrioventricular hihia II degere;
• symptomatic hypotension;
• hāpai keiki, ke keiki;
• decompensated naʻau ole - naau hoʻokō 'ole' II B-III.

I hana like me ka contra allergic naoh ma muli o ka loaa blocker. Inā kekahi lāʻau allergy e hoʻomōhala ana i, ka hope lāʻau a hiki i kekahi ke hoʻoponopono i ka pilikia.

'Ole o ka lapaʻau pono o ka ai'

I ka angina ai 'me ka nui loa emi i ke alapine (frequency) o ke angina ho'āhewa wale, a me ko lakou ikaika, emi ka likelihood o huʻi coronary hanana. Ma CHF lapaʻau me ka Hoʻokolohua-blockers me ka ACE nā mea kūpale a me diuretics mau, piʻi pū ola expectancy. Lapaʻauʻia nā mana i ke kaōhiʻana tachyarrhythmias, a hoʻokaumaha pinepine ectopic kui iho oe a ma ka ventricle. Ma huina, dala, e kōkua kū i kekahi symptoms o ka naau maʻi.

Hopena a e pili ana i ka Hoʻokolohua-blockers

"Carvedilol" a me ka "Nebivolol" - o ka maikaʻi loa Hoʻokolohua-blockers. Ka papa inoa o ka ai 'e ho'āʻo preferential haʻawina o Hoʻokolohua-receptors, complements i ka papa inoa o ka papa kuhikuhiE therapeutically nui ai'. No ka mea, ma ka lapaʻau me ka hana pono e hoʻohana 'ia kekahi ma ke kolu o ka hanauna, o "Carvedilol" a me "Nebivolol" a puleʻAmelika, e wae no ka Hoʻokolohua-1 mea loaʻa ai', "bisoprolol", "metoprolol". A hiki i keia la, i ko lakou noi e leie aku oe i ka pāʻana hypertension, a no ka pono naau maʻi.