Protamine sulufahate: Description a me ka Mea hoʻohana

He aha mea he lāʻau 'waiwai like protamine sulufahate? olelo ao no kona hana, e like me ke kinona, a me ka hoike ana o na dala e e helu 'ia ma lalo nei.

Haku mele 'ana, hōʻikeʻano, ano

He aha ka protamine sulufahate? Ua kākoʻo pāʻoihana Ua hookuu like me ka yellowish a colorless aniani moakaka wai a manao no intravenous hooponopono. Ka hoʻomākaukau me ka nānā 'ana i kēia k i ka ia inoa, a hou maupaʻa i ka wai no ka pahu kui.

Ma ke kuai ana o ka "Protamine sulufahate" ua lako i ka hue i e hoonoho iho i loko o ka halepaahao outline mai Tewetewe koloriside ho film, a i piha i ka pepa pahu. ¶ A i loko o ka AEeAaOA ua kau olelo ao no ka hoʻohana a me ka ampoule opener.

Uluwehi O hana

He aha ka protamine sulufahate? Alakaʻi ai ia mau moʻolelo i kēia heparin hoa (kekahi). 1 mg o ka waiwai hiki o neutralizing i ke ahonui o ka koko o kahi o 80-115 Iu o heparin.

Hana mai, a hōʻike 'o ia hoʻi ma hope o ka pahu kui intravenous hoʻomaka koke, a mau no e pili ana, elua no hora. Complexation o ka lāʻau aie a hiki i ka nui loa o ka cationic pūʻulu e nakinaki i ka anionic-oaio? A heparin.

E like me na olelo o ka protamine sulufahate i loko o kānaka ua? Eiiieaena heparin-protamine, a mai hemo mai e wehe i ka la mahope.

Ma overdose kēia 'o ia hoʻi ka hoomanawanui hiki ke me ka nui loa hoemi koko clotting, mai eu Agena hoʻomanaʻo hōʻike he kiʻekiʻe anticoagulant hope.

Pharmacokinetics ano

He aha loaʻa kinetic waiwai o ka heparin protamine sulufahate? E like me ka poe akamai, e loaʻa pharmacokinetic waiwai o ka lāʻau i ole ua? Anoee. Nolaila, aole lakou e i na poe i loko o ka manuale.

Nāʻikepili no ka pāʻoihana

Ma kekahi mau hihia, i ka hoʻomanawanui intravenous pāʻoihana "Protamine sulufahate" hiki ke lanakila? Noi ana i keia mea ua hōʻike:

• muaʻoki kino i loko o ka lawe heparin no ka pākōlea hana kanaka;
• ma hyperheparinemia;
• no ka kahe ana ke koko 'ia ma muli o ka heparin overdose;
• ma hope o ka hana ma luna o na moku ke koko a me ka naʻau me ka extracorporeal holo.

Kapu pāpā i ka mākaʻikaʻi pāʻoihana

Uluwehi O "Protamine sulufahate" (ke kuhikuhi, e kuai ia pono i koi 'ia ke kauka) ua contraindicated i loko o ka kēia hihia.

• me ka thrombocytopenia;
• kiʻekiʻe pā lonoaʻili i na kumu o ka lāʻau;
• loa hypotension;
• congenital ole idiopathic hyperheparinemia (i loko o kēia moku'āina o ka lapaʻauʻia mea ineffective, a ua hiki no hoi me ka nui loa ka hōʻoi 'kahe ana ke koko);
• aaieieno? o insulina a me ka 'ē aʻe ai' i loaʻa i ka protamine sulufahate;
• allergic reactions i ka iʻa me nā huahana, a me ka mōʻaukala;
• adrenal insufficiency.

Mākou hiki ole ke olelo i ka ike ana o ka 'inikua pono o kēia koʻi i loko o nā keiki mea i kaupalena'.

Ma hāpai keiki, a lactation "Protamine sulufahate" hiki ke hoʻohana. Naʻe, i kēia E e hana wale i ka hihia, ina o ka hopena o ka iapaau ana mea me ka nui loa ma luna ma mua o ka mea paha kamepiula a hiki i ka fetus a keiki.

E hoomakaukau ai "Protamine sulufahate": kauoha no ka hoʻohana

Nānā akula au i kākoʻo pāʻoihana ai e haawiia mai e lohi IV drip paha bolus. Pela ka uku o ka hooponopono E ole oi 5 mg no minuke. Aku hoike o ka lāʻau hiki i ka hoʻomanawanui anaphylactoid naoh.

Laʻau heluna o ka medicament hilinaʻi nui ma ke ano o ka hooponopono. Ka pōpilikia mahele lāʻau E e ia ka pono i loko o 300-500 ml o 0,9% ikaika paʻakai koloriside pāʻoihana. Ua Ua pololei papaia e komo hou ma mua o 150 mg o ka lāʻau no 60 mau minuke.

• Me ka bolus ka pahu kui laʻau heluna o ka protamine sulufahate ua hoemiia ke kaumaha ma muli o ka manawa e i hala, mai ka hooponopono ana o heparin. O ke kumu ho i ka mea i ka la mahope ua noke wehe 'ia mai ke kanaka kino.
• Inā heparin ua lawelawe intravenous drip, ia mea pono e hooki aku i ka infusion, a hoʻohana 'ia ma kahi o 20-30 mg o protamine sulufahate.
• Ka wā subcutaneous ka pahu kui o ka heparin laʻau heluna o ka protamine sulufahate 1-1.5 mg 100 Iu heparin. Pela ka mea mua 25-50 mg E e lohi lawelawe intravenously, a me ka nui o ka i koe, - intravenous drip no 8-17 hola. Ua mea no hoi e hiki intermittent hoʻoponopono, akā, ka mea, e hoopai ikaika ka mālamaʻana o APTT.
• I ka wā o ka ho'āla 'uao i ka hihia o extracorporeal holo pāʻoihana noʻonoʻo laʻau heluna mea 1.5 mg i 100 ME heparin.

ʻO kā mākou lōʻihi like 'ole o ka Inc o na dala, he 3 mau lā.

Hana ma-ke ano

E hiki anei i ka protamine sulufahate e i adverse reactions? Manual Hawaii i loko o mau keia k ua kŘpa a maikaʻi tolerated e hoʻomanawanui iki mai. Eia naʻe, ma kekahi hihia, e hiki nō i adverse 'ole ma ka aoao o ka'ōnaehana paleʻea, mea'ōnaehana mānowai koko a me ka digestive nenoai, e like me kaʻili:

• bradycardia, he ka ho'ēmiʻana i loko o ke koko,;
• ka luaʻi, a nausea;
• ka ohane ame, ili poʻe noʻonoʻoʻole, kūpono 'ana o anaphylactoid reactions;
• e manao ana wela, e manao ana pōkole o ka hanu, a me flushing o ka ili.

Overdoses a AaOIeIOUIeXAOAaIN me nā ai '

Nānā akula au i kākoʻo pāʻoihana manaoia no intravenous hooponopono mea incompatible me penicillins a me cephalosporins. Ua haawiia i ka mea, o ka hoa, haʻahaʻa hakakino kaumaha heparins, ʻeleu lāʻau e hoonui i ka lōʻihi like 'ole a me ka nui o ka hana o ka non-depolarizing Muscle relaxants.

An overdose o ka lāʻau i ke pili me ka kahe ana ke koko. O ke kumu ho i ka mea i ka waiwai ma ka nīnau i ke kiʻekiʻe anticoagulant hope. Ma keia hihia, e hali ana mai symptomatic kanaka ua koi 'ia.

kiko'ī

He aha oe e ike mua oe e komo aku e like me ka pāʻoihana like protamine sulufahate? Kilo'ōlelo aku nei au i ka hana ana o keia k E e pili loa ua hoʻonānā e ke kauka nana pono mau kanaka hoʻoponopono i ke koko clotting hoʻomanawanui.

Ma mua o ka hoʻokomo 'ia' ana o ka lāʻau pono e hōʻoia 'kūpono hoomanawanui ka koko ka leo. O ke kumu ho i ka mea i hypovolemia me ka nui loa maoli ka pilikia o ka'opi.

Waho pūnaewele kumu o ka lako o nā keʻena kūʻai lāʻau lapaʻau, ka holopapa ola

Ina paha o ka 'elele kuai ma keʻena kūʻai lāʻau lapaʻau lāʻau "Protamine sulufahate'? Beauty ma Roma paha Lūkini 'ōlelo, eʻoiaʻiʻo, e hōʻike i ka pharmacist, ai ole ua hookuu i ka waiʻona.

Ho'āhu hoʻi noonoo pono i ka loaa ole o na keiki a me ka palekana mai ka lń ma ka lewa mahana mea ma waena o 4 a me 10 degere. Ua E hoi e kaulana ole e i ka intravenous pāʻoihana "Protamine sulufahate" ma kekahi hihia pono paʻahau.

Holopapa ola o keia k he 4 makahiki, mai ka lā o ka hana. Mai hana ia ma kela aoao o ka pau ana o keia wā.

Uluwehi O analogues a me nā hōʻike manaʻo e pili ana ia

Analogues ma ka hōʻike 'ana no na mea paahana, ua ole loa na mea he nui. Ke intravenous pāʻoihana hiki auou caiaiai ia e ai 'e like me "Protamine" a me "Protamine-Verein".

Me ka pili ana i ka consumer nāʻana, kokoke e pau no ia i maikaʻi. "Protamine sulufahate" - keia mea he loa efficient pono a me ka mea i loaʻa i ka a pau. Ua Ua keia manao ua kaʻana 'ia e ka hapanui o nā mea maʻi. Ka mea, koi i keia ka lapaʻau 'aʻole e haawi heparin e inhibit i ke kaʻina hana o ke koko clotting, ka hoʻomaikaʻi i ka hoʻomanawanuiʻanaʻano ma kaumaha kahe ana ke koko.

Like ai i ka pono o keia k nā kona kokololio, a hooloihi ae i hopena. Eia kekahi, e hoʻokō i ka pākōlea ia i ka hoomanawanui ua koi 'ia e lawe mai loa-makahiki lapaau. ʻO kā mākou wā o ka hoʻohana 'ana i kēia k mea i na la ekolu.