B12-deficiency anaemia: symptoms, kumu, lapaʻau

B12-deficiency anaemia - heʻano mea pepehi maʻi, a ua pili i ka hoʻohuikau 'o ka maʻamau koko ho okumu keʻano o ka hanaʻana i hana ku e aku i ka backdrop o cobalamin deficiency i loko o ke kino. I kēia lā, he nui loa kanaka i hoihoi i ka ninau e pili ana i ka Makaʻu ma lalo o ka aoao o ka anaemia pu ma symptoms, a pehea ka maʻi.

He aha mea he maʻi?

I ka mea, B12-deficiency anaemia uaʻikeʻia ma kekahi mau hua'ōlelo - ole ia pertsinioznaya megabloblastnaya anaemia, pernicious anaemia, a Addison ka maʻi-Birmera. Kēia maʻi ua pu e emi ma ka helu o kaʻulaʻula koko keena, i mea ku pono i ka deficiency o ka wikamina B12 (cyanocobalamin). It E e hoʻomaopopo i ka pakahi aku la ia ikepili koʻikoʻi i ka nele o keia waiwai mea ole wale i ka 'ole o ka iwi lolo, akā, i ke aʻalolo'aʻaʻa, a, ma ka mea, i ka maʻi pilikia loa.

Ma ka hapanui o hoopii, e diagnosed nā mea maʻi B12, folicʻakika deficiency anaemia, ma i ka malama nele o folicʻakika. Ka mua symptoms o ka maʻi i ua hōʻike kŘpa nei - i ka 1855, i ka 'ōlelo Pelekānia kauka T. Addison i ka noiʻiʻana i kaʻike maʻi. A ma ka 1926, noiʻi W. Murphy, J. Will a me Ioane. Minot i loko o kā lākou noiʻi i hōʻike mai i nā symptoms hoopaakiki mai oe, ina e kikokiko i loko o ka hoʻomanawanui i kaʻai o ka maka akepaʻa.

I ka papa kuhikuhiE kumu o ka wikamina B12 deficiency anaemia

Koke ia mea kumukuai 'ana i kumumanaʻo mea, ua nui na kumu o keia ano o ka anemia. Kekahi o ia e pili ana i ke ala o ke ola, oiai kekahi poe - me nā loli i loko o ke kino.

• Mua oe Pono e hōʻike i ka ai-kapaia'aiaola deficiency, a ua kauoha aku e lawaʻai ana o ka wikamina i loko o ke kino ma ka ai. No ka laʻana, i kēia maʻi hiki hoʻomōhala ma luna o ke kāʻei kua o ka hooke ai ana a me ke kanana 'vegeterianstva. Ma kekahi keiki, keia palapala o ka anaemia ike i loko o ka hanana i ke keikiʻai makuahine aole e holoholona huahana.
• Ma kekahi nā mea maʻi he mea he 'aʻe' ana o ka mea maʻamau omo cyanocobalamin.
• Kumu o B12 deficiency anaemia hiki e ku pono ana i ka nele o ka ai-kapaia kūʻiʻoo ololi Castle. Kēia mau luna 'waiwai i ua hookuu intestinal mucosa, pili e cyanocobalamine a hoʻolako kona omo. I huli ai oe, o ka nele o keia waiwai hiki ke kena ae la ia e kekahi congenital anomalies, e like me autoimmune maʻi. ¶ A, i ka wa a kela mall loli i loko o ka opu, e like me gastritis,ʻoki lāʻau lapaʻau hana, a no laila, ma luna o ka nele Castle ololi malama. D.
• 'Ākena Makaʻu Hiki ke wahi no hoi, a heʻano o nā loli i loko o ka 'ole o ka intestinal'aʻaʻa i ua ike i ke alo o ka hikoko, a me ka hoʻomōhala ana i like me ka hopena o keʻoki lāʻau lapaʻau resection o ka na naau oʻu.
• Omo na naau oʻu kuleana pili i ke ĸokoĸa ana nä pane ma ka alo o ka dysbiosis, kahi o ka haku mele 'ana microflora hoʻololi.
• Ma kekahi mau hihia, cyanocobalamin, i ke kino a me ka ai ka paka ma ka "occupants"'ē aʻe digestive'ōnaehana, e like me pathogenic koʻohune a me na ilo.
• 'Ākena Makaʻu hiki nā ake a me ka hakuʻala mai e like me kā lākou kāʻei kua ua pinepine malama mahuahua i auaaeaiea o ka wikamina B12 a me kona hoʻohana mea kāpili.
• Deficiency i hoʻomōhala i loko o ka hanana i'aʻaʻa a me nā loko omoʻia he nui loa o ka wikamina. A like kŰia ua malama, no ka mea hoike, ma ke alo o ka hikiwawe loa e ulu ana Ka maʻi 'aʻai. 'Ākena Makaʻu nā hormonal loli a me kekahi endocrine kāna hana, a me nā maʻi pili me ka poho o ka hana ulaula koko keena.

Ke pathogenesis o ka maʻi

Pehea ka B12-deficiency anaemia? Ke pathogenesis o ka maʻi mea pololei nā i ka walaʻauʻanaʻoihana o ka cyanocobalamin. Kēia wikamina Radio nui i kūlana ma ke kaʻina hana o ka hematopoiesis. Kona deficiency hiki aku ai i ka manaʻo me "megablastoz". Ua Ua pu ma ka hoʻomāhuahua o nui ano o platelets, a keʻokeʻo koko keena, e like me kā lākou premature ka make i loko o ka iwi lolo.

Eia hou kekahi, wikamina B12 mea he cofactor i loko o ke ki kūkaʻi reactions i mea nui i ke ola o nā aʻalolo keena. I mea no ke aha la mai kona nele ko mākou hopohopo kahua poino.

B12-deficiency anaemia: maʻi symptoms

Oia maʻi ua pu ma ka nui o symptoms, a i ana hui i loko o ka papa kuhikuhiE pūʻulu ekolu.

Mua, e mau kamailio e pili ana i ka anemic maʻi pale e hoʻomōhala ana i ku e mai i ke kāʻei kua o ka hoemi i ka nui o ka ula koko keena. Initially, e hoomanawanui i ohumu o loa nawaliwali, kokololio luhi, a me ka na hiohiona ka ho'ēmiʻana i ka hana. E like me ka maʻi progresses laila kēlā wā i kēia wā aicieeaao tinnitus a me ka pōniuniu, a i kekahi manawa e maʻule hou ihola nō. Maʻi kanaka hoi nana i ke ano o ka "nahu" ma ke alo o kona mau maka. hiki i na hoailona o ka anaemia nā naʻau palpitations a me ka loa pokole o ka hanu e ana a me ka iki physical exertion. I kekahi manawa, he meaʻawaʻawa loa, hou ae la oiaʻeha i loko o ka pahu.

O ka holo ana, a me ka nele o ka wikamina malama a me kāna hana o ka digestive nenoaiu. Ma kekahi, ua ike hoʻomanawanui iki mai i ka hana keaka emi ma ka ikaika loa ka makemake, a me ka hopena, kino ke kaumaha me keia poho. Recurring nausea a me ka luaʻi i lawe mai i loko o ke kanaka ka ola o ka puu o ka hana a he leo. Eia hou, i ka hiki aʻe 'o ka noho - loa pinepine ia mea lōʻihi constipation. Loa ano, a ua manaoia e hoʻololi i ka 'ōlelo, kona ili ua o Keʻei, a lilo olinolinoʻulaʻula, a me kekahi manawa ulaula hue.

O ka holo ana, keia mea,ʻaʻole a pau o nā hoʻololi e pili ana i ka B12-deficiency anaemia. Symptoms hou a me ka ua'emi nenoaia. Ma ka wahi mua ma laila mea i ka pio ana o kaʻike ākea nā aʻalolo. E hoomanawanui i hai mai i kaʻawaʻawa loa tingling i loko o nā lima a me nā wāwae, e like me? Aiaiiuie numbness. Ua ulu Muscle nawaliwali. he gradual loli ma ka gait ua malamaia ma ka pili ana me ka oolea o nā wāwae - ka mea, lilo hou lolelua.

Hooloihi ae i deficiency o ka wikamina B12 hiki aku ai i ka spinal hawewe, a laila, i ka lolo. Nā symptoms o ia kāna hana i ke e lauwili. No ka laʻana, pōʻino i ka olona, ma ka spinalʻula, IeAUPIIe, IAa IO hiki aku i ka hookaheia'na o ke pā lonoaʻili - he kanaka hou Kahalaopuna na kuekueni o ka ili (loa pinepine e loli ai i ka ili ma luna o nā wāwae). Kekahi e hoomanawanui i hoʻomōhala convulsions. Akā, irritability, uncontrollable naʻau i loko loli, kāna hana o ka pokole o ke ano hoike lolo ka pōʻino. I ka hele ana o Inc, i ka hoʻomanawanui i hāʻule i loko o ka coma.

ano o ka maʻi

O ka holo ana, loaʻa nō kekahi mau ano o ka Mea Maluna o ka maʻi. He nui i ka ike i loko o ke kālā no lapaau B12-deficiency anaemia hiki ia i mau hoailona ia mea, ke kaumaha ma muli o nā kumu o:

• Ke iniiaiie ano o ka maʻi ua IeAUPIIe, IAa IO me kekahi aaiaoe ano o ka meaola pili. Ua ua ia he B12-deficiency anaemia i keiki na kamalii uuku ia lŘlŘ loa pinepine.
• Ka haumāna ano o ka maʻi e hoʻomōhala ana i mua i loko o ke kaʻina hana o ka ulu ana mai a me ke ola ana o ke kanaka, ma lalo o ka aoao o ke kumumea mawaho a maloko 'ia.

anemia ke kahua

I ka papa kuhikuhiE symptoms o ka maʻi e pono e kaukaʻi ma ke kahua o kona ulu ana. Ke oolea o ke ano o ka hoʻomanawanui ua ana ka manao o ka nānā 'ana ma luna o ka helu ana o erythrocytes (ʻulaʻula koko aeee) i loko o ke koko. Kaumaha o keia huahelu, eia ekolu kuʻina o ka maʻi.

• I ka mehana anaemia, ulaula koko aeea helu papa koa mai ka 90 a hiki i 110 g. / Ho'āo ai.
• Ka oolea palapala ua wehewehe aku e ka nui emi ma ka helu o kaʻulaʻula koko keena - mai ka 90 a hiki i 70 g. / Ho'āo ai.
• Inā ke hoʻomanawanui i ka 'ulaʻula koko aeea helu o 70 g. / L a emi, a laila ia mea he nui ke ano o ka B120-deficiency anaemia, i mea loa pilikia i ke ola kino a me ka hiki ke ola.

Pehea pilikia keia ano o ka anemia? hiki complications

Anemia, wikamina B12 deficiency i loko o ka wa e kaawale aku o ka 'eleu lapaʻau hiki e'āina weliweli. E like me ua oleloia, kuhikuhi ka nele o keia waiwai e loli ai i ka'emi ko kahua. Complications o kēia 'ano o ka anaemia nā ka spinal kaula a me kaʻike ākea nā aʻalolo. I ka huli, e pu mau me na haunaele ma discomfort a tingling ma nāʻaoʻao, a me ka piha hapa lilo ana o ka waiʻona ma, fecal incontinence paha incontinence.

E kū'ē i ke kāʻei kua o ka maʻi cyanocobalamin deficiency worsens i ke kino a pau - e i keʻano o ka maʻi o nā puʻupaʻa, naau, a me nā loko. I kekahi manawa, amid kaʻoi ka ho'ēmiʻana i loko o ka helu o kaʻulaʻula koko keena hoʻomōhala lolo hypoxia, e alakai i ka pernicious coma.

Inā e hoʻomaka lapaʻau i ka kakahiaka nui ke kahua, laila, a pau na luna complications hiki ke käpae '. Late ulu mau Inc hiki hoʻopau wikamina deficiency, akā, auwe, loli ma ka'emi'ōnaehana mea ua irreversible.

Hoikehonua, ano o kaʻike,

Ma ke alo o ka luna symptoms oe e maopopo leʻa ike i ke kauka. Ma hope o nā mea a pau, wale he akamai ke pololei kuhikuhi i ka maʻi. No ka hoʻomaka ua i 'inikua mōʻaukala. B12-deficiency anaemia ana e hoʻomōhala ana i lalo o ka aoao o ka likeʻole mawaho aʻe, no laila, i ke kauka e nīnau 'ike e pili ana i ke ahonui o ka ola, me kona mana, a no laila, ma luna, D. I ka wā e hiki mai, e ka physical hōʻike. Ma nā mea maʻi me ka like maʻi, e like me ka rula, ka mea hiki ke ike haikea ili. Pinepine ka mea, he emi i loko o ke koko, a me ka palpitations.

O ka holo ana, hope ukali ma nā haʻawina, me ka i oe ke ike ai i ko ole ai he mea kekahi B12-deficiency anaemia. A koko hoao aku me ka maʻi maopopo emi i ka helu ana o erythrocytes a me kā lākou a hiki (reticulocytes). A me keia he mea he emi ma platelet helu. O ka ihu, hoemiia ka nui o ka hemoglobin i loko o ke koko. Biochemical Ka Ikepili o ke koko hiki i hoʻolako waiwai 'ike. A hiki i keʻano o ka maʻi anaemia, he mea he mahuahua i loko o ke koko o ka pae bilirubin a me ka hao.

ʻike, o B12-deficiency anaemia kikowaena nā kaʻina hana. Ma kekahi, ua hana iwi lolo pa (i loko o ka hapanui o na hihia lawe sternal puncture) no ka keʻena hoʻokolohua noiʻi. Eia hou, i ka hoʻomanawanui lima ma kālailai o ka mimi a me feces. Hōʻike i electrocardiography, electroencephalography, Me tomography, a me kekahi manawa kekahi o ka mea'ē aʻe hana - kēia mau ho'āʻo ma mea e pono ai e Loiloi i ka loa o ke poho i kekahi hui 'oihana, e like me ka hooholo i ke kumu o ka anemia.

B12-deficiency anaemia: lapaʻau

Ke kauka hiki e i ka hoʻokō hana maikaʻiʻole ma hope o piha meaola ninaninau wale. No laila, aha Inc pono B12-deficiency anaemia? Lapaau hoʻomaka me ka hoʻopau o ka nń ku kumu o ka maʻi. No ka laʻana, ka wā lawelawe i nā mea maʻi helminthic infestations antiparasitic Luna, a ma ke alo o kaʻeho -ʻoki kino.

Eia hou kekahi, ia mea pono e compensate i ka shortage o cyanocobalamin. Ma ka mea mua mau lā o ka wikamina pāʻoihana ua injected intramuscularly. No ka mea awelike makua kela la i keia mahele lāʻau mea mai ka 200 a hiki i 500 micrograms. I loa aku ana ua mahuahua no 1000 mcg i ka nui o ka lāʻau - ka noaia hoopili aku i na la ekolu. I a hiki i napoo hou emi ka mahele lāʻau i 100-200 mg - injections i haawi mai ai koke i ka mahina no 1-2 makahiki.

Maoli ai, ia meaʻano nui e e i kaʻai pono e komoʻai waiwai ma ka cyanocobalamine a folicʻakika - ia mea kuhikuhi i ke ake, ai a me ka hua.

Loa anaemia noi aku ka manaʻo a hoʻopiha nō ia ula koko aeea helu. No kēia mea, nā mea maʻi i ula koko keena mai hâʻawi wale koko. ʻO ia ke kaʻina hana no ka pono ai ka wā anemic coma.

E like me ka 'ikepili helu, ka prognosis no nā mea maʻi mea he maikaʻi. 'Ia e wale ia mau hihia ma ke kanaka imi kōkua ma ka mea nui ana, e like me ka hoihoi mai i ka loli wahi o ka'emi'ōnaehana mea,ʻaʻole hiki.

He nui ka hoʻokō ano o ka Kāohiʻana?

E like me 'oe ke ike, B12-deficiency anaemia - he maʻi like pilikia loa. He nolaila, nui e ho'āʻo i ka pale aku ia maʻalahi. A ma keia hihia, pono-i hanaʻai ka mea nui. E mālama iʻai waiwai cyanocobalamine hele mau i loko o kou 'ike no. Ma kekahi, ua loaʻa wikamina B12 i ka hua, ai, ake a me ka haleʻuwī waiū me nā huahana.

Nā maʻi o ka gastrointestinal'āpana i manawa e pane i ka lapaʻau - ia mea mau Kuleana e hooko me ka Kauka ka'ōlelo aʻo a me ka mai e haawi aku i kā lākou mau lāʻau. Mai manawa i ka manawa ka mea, ua pono i ke kāohi ana e lawe multivitamin pono a pau o (kela eono mahina).

Ma hope oʻoki kino i ka wehe 'ana o ka naʻau liʻiliʻi a me ka'ōpū kauka ua koiia e hoonoho i kekahi ahonui cyanocobalamin hoomakaukau ana i kūpono mahele lāʻau.