"Dopamine" - He aha ka mea? "Dopamine": ke aʻo, noi, kuai

I ka lāʻau "Dopamine" nana e like me ka mea pōaka pauka o keʻokeʻo ano me ka māhunehune perceptible ala o hydrochloricʻakika. Kēia palapala ka mea, i loko o ka palapala o ka hydrochloride. "Dopamine" - he waiwai wailana i loko o ka wai a me ka waiʻona. Ua ua loli ana ma alkalis, kela oxidizing konohiki a me ka hao paʻakai. Nāʻikepili a me contraindications i ka hoʻohana 'ana i ka lāʻau "Dopamine", ke aʻo ma luna o kona hoʻohana' e waiho i loko o mākou paʻi puke.

'O ia hoʻi hoopukaia like infusion pāʻoihana kiaʻana i kāna.

pharmacological ano

"Dopamine" - he waiwai, he neurotransmitter. Ma ka metabolic waiwai ana o dopamine mea he precursor o adrenaline a me ka noradrenaline. Ke k loli ai i ka like receptors, a ma kiʻekiʻe nā hoʻohui like hoʻokāʻoi aʻe ana i hana α- a me ka β-adrenoceptors. "Dopamine" ua hana nona:

• holomua o kaʻike ākea vascular e kū'ē'ē mai;
• mahuahua ma systolic ke koko;
• stimulation o ka ka naau kōmi;
• mahuahua cardiac auaiaea;
• Nā loli ma ka naau kōmi;
• nui ka oxygen lako.

"Dopamine" kekahi hoʻokāʻoi aʻe ana i ke koko i loko o ka ipu a ka lolo, naau, a me nā puʻupaʻa liʻiliʻi. Hoomahuahua ae la lakou glomerular kānana ana a me ka paʻakai excretion ma ka hakuʻala.

"Dopamine" - i ka hoʻokēʻai-hana lāʻau. Mahope o 5-10 minuke ma hope o au / V infusion hana welau. Ka hapa-ola - ka hola mau minuke. Hapalua o ka waiwai pāʻani aku me ka kumuʻiʻo i loko o ke koko wai koko. Ka lāʻau 'ae kokololio pūnao kaʻina hana ma nā puʻupaʻa, ake a me ke koko wai koko no ma ka aoao o ka Mao, a catechol-O-methyltransferase i ka moku'āina o AEeOEXAaI metabolites, a ua' Imi hua mai ma ka hakuʻala. A hapaha o ka pono o ka mahele lāʻau ua hoohuliia i ka norepinephrine i loko o ka adrenergic nā aʻalolo kupu ma ka hopena. Aie i kaʻeleu hoʻopau mea,ʻaʻole he hoʻomāhuahua o ka lāʻau i loko o ke kino o ke kanaka, a hiki ma hope o ka manawa lōʻihi o? Eaia.

"Dopamine": palapala noi

Nāʻikepili no loaa:

• Mai Ke Kula Kaiapuni 'ano o ka hawewe, e like me ka traumatic, cardiogenic, postoperative, hypovolemic, endotoxin.
• Huʻi vascular a me ka naʻau 'ole.
• Low cardiac auaiaea.

"Dopamine" me cardiogenic kŰia kūikawā e pono ai, ka mea maoli he myocardial contractile kuleana pili i.

Ka lāʻau 'Ua lawelawe intravenously. 125 a me 400 ml o elima pakeneka pāʻoihana o ka paʻakai koloriside a monakō koko pāʻoihana e pono ai ma ka 25 a 200 mg niioaaonoaaiii. Penei, 1 ml o ka pāʻoihana loaa 200 a me 500 .mu.g waiwai. Inā ka hoomanawanui hiki ole ke lawelawe nui puke o ka loli hiki ke i hou i kia pāʻoihana no laila, ua 1 ml o 800 micrograms ua "dopamine". E hana i kēia, lawe 200 mg no 250 ml o ka pāʻoihana. I ka uku o ka hoike kīnā 1-4 ug / kg no minuke i ka awelika kino ke kaumaha o 70 kg (2 me 11 paka ua o ka 0,05% pāʻoihana 'ole mai ka 1.5 hiki i 6 paka ua o ka 0.08% pāʻoihana). Na pākōlea laʻau heluna - mai ka 5 a hiki i 9 mg / kg i ka 1 min. Laʻau heluna "Dopamine" 10-15 .mu.g / kg no minuke mea pono ma ka vasodilation a me ka hypotension. hiki e māhuahua ai ka hooponopono ana i ka 18 .mu.g / kg no minuke. Ke infusion i wahi me ka haʻahaʻa, a uhi i ka wā mai ka 2-3 hora i 1-4 lā a hou. Ka mahele lāʻau no ka lā,ʻaʻole e oi aku 800 mg. Me ka hoʻokomo 'ia' o "Dopamine" ua paa ECG ka mālamaʻana. Hoʻoholo 'ana o ka mahele lāʻau, a uku o ka aaieieno? Ua e like me arterial puʻe, naau ana, cardiac auaiaea, naau i kela a me diuresis, Inā hypotension Aʻole e kū aʻe, a ua hoʻemi mimi auaiaea, E hoemiia ka mahele lāʻau e.

Contraindications

Ka lāʻau 'Ua contraindicated i loko o ka hanana o ka pilikia e like me:

• arrhythmia;
• pheochromocytoma;
• prostatic hypertrophy;
• panina glaucoma.

ʻaoʻao waiwai

I ka hoike ana o ka waiwai i loko o nā māhele nui, he nui kiʻekiʻe o "Dopamine" hiki iʻaoʻao waiwai, me:

• tremor;
• tachycardia;
• vasospasm;
• arrhythmia;
• 'aʻe' ana i ka ÷ naehana hanu pāpana;
• anginal a me ka headache;
• psychomotor manaʻo pīhoihoi ;
• Other hoikeana Adrenomimeticalkie hana.

Mai ka hoʻopau o ka "Dopamine" Uaʻeleu, ka luna symptoms nalo ina haahaa i ka mahele lāʻau 'ole nōʻoe, hooponopono o ka lāʻau. Inā ka pāpana ua wawahiia, ia mea pono e hoʻohana antiarrhythmic ai ', a me "Verapamil", "lidocaine" a me na mea e ae. Extravasation pāʻoihana "Dopamine" hiki alakai i necrosis o ka subcutaneous adipose'aʻaʻa, a o ka ili.

Cautions

"Dopamine" i hāpai keiki i ke kau wale ka wā pololei e pono lapaau no ka makuwahine, a me ka pākōlea ia mea ma luna ma mua o ka pilikia a hiki i ka fetus.

Hou pāʻoihana e i ka aniani moakaka hionapāʻili a me ka nele extraneous hue.

I ka wā hoʻokahi lapaʻau a me nā ai '

Ka lāʻau 'hiki e ia i loko o laua me ka cardiac glycosides a me diuretics (e laʻa me, furosemide a me ka' ē aʻe). Hypovolemic nń pono ka hoike ana o "Dopamine" a me ka a pau, ke koko, wai koko a me ka wai koko ae pani ai.

Mai lawe "Dopamine" i ka ia manawa me ka "cyclopropane", Mao nā mea kūpale a me nā konohiki no ka anesthesia me ka Halo ( "Halothane" a me na mea e ae).

Papa wiliʻai Aloha hoʻomanaʻo unacceptable me kona'ākilikai pāʻoihana o'ē aʻe ai '.

"Dopamine" - i ka lapaʻauʻia i ua hoʻohana wale ma luna kuhikuhi. Kona kumukuai hilinaʻi nui ma luna o ka laʻau heluna, a me ka helu o nā ampoules i loko o ka AEeAaOA, HEN, mai 80 a hiki i 300 rubles no pack (5-10 ampoules).