Na Ke Kumu no ka hoʻohana - ampicillin

Muli o kona kulana he ana aku nei, ia la ia mea i ka papa kuhikuhiEʻano papa hana o ka adaptability oʻano o ka koʻohune i antibiotics i ka β-lactamase a me kā lākou me nā huahana. Ka mea, ua nui loa kona mana ma ka hoʻopukaʻana i ka make ana o ka aiiay apo antibiotics a me kaʻaneʻane ana kā lākou pākōlea hopena. E lanakila i kēia io hookoia no, ka mea, ua ulu a ua kokoke makaukau Nine Inch hui i inactivate β-lactamase mea kuhikuhi clavulanicʻakika mea haʻilula keimikala sulbactam a me ka tazobactam.

Mau i huiʻia nā like oihana mua o ka ai-kapaia penicillin ingibitorozaschischonnyh - hui ai ', i nā penicillin antibiotic. Lohe nuiʻia examples o ka hoomakaukau i ampicillin-sulbactam, amoxicillin, ticarcillin a me na mea e ae aha i ka pae ana o penicillins. Lākou hoʻohana Ua pono no hoi, no ka mea, e ae ke hana me hapa o ke ākeaʻano o ka pu ana o ka cephalosporin o III hanauna, oiai ka laulā o ka hana 'Oponopono kālele ma ka pae kiʻekiʻe.

Ma nā ana, e hoʻohana 'ia i loko o na mea he nui ke kālā no ai' ec i ka haku mele 'ana antibiotics a me nā mea kūpale o β-lactamase, aia no he iniiaiie aayoaeuiinoe e noho penicillins, a ua kokoke loa i pohala ae la lakou i ko lakou mau pākōlea hopenaʻoi loa i ka paioʻana o ka hapanui o ka ike no ka staphylococci i keia la anaerobes a me Gram koʻohune. Eia hou kekahi, ma ia mau mea haʻilula keimikala ua hoʻonui lākou antimicrobial pae. Oia lāʻau no i ka ampicillin / sulbactam, a ke kaumaha ma muli o ka Hookah nō hiki e hua mai ma lalo o ka inoa a me unazin Sulatsillin.

Kēia ka lapaʻauʻia nā ampicillin a me ka sulbactam, i mea i loaʻa i loko o ka lākiō o ka 2: 1. E like me hōʻike ma ka manual, ampicillin a me ka sulbactam i loko o kēia makaukau ole maoli ka paleʻana β-lactamases i ke 'ano haʻi haʻawina iā Neisserial a me atsinetobakterov.

IeAUPIIe, IAa IO no na lāʻau e loaa ana ia sultamicillin, haku o ka sulbactam a me ka ampicillin. O na papa io o ka loaa ana paka i loko o ke kino. A laila, i ka naoh o hydrolysis a me ka hui ole ec i ka lāʻau a me ka ampicillin sulbactam, a hoʻokāʻoi aʻe ana i ka bioavailability o ampicillin a kiekie ae 'ilikai i ka ua i hiki aku i ka wa e loaa ana ka like mahele lāʻau o ka loina ampicillin.

Muli o kona kulana he ākea pae o ka haʻawina, a me keia k. No laila, ua hōʻike 'ia i loko o nā mea palahēhē o ka mea koʻohune me Kinohi TTP ka hoʻohana a loa ai', sinusitis kekahi mau kinona a me etiology. Ka lapaau Ua koi 'ia ma nā maʻi o ka lalo naehana'āpana: maʻi bronchitis, pneumonia.

E like me ke aʻo no ka hoʻohana 'ana, ampicillin me ka sulbactam maʻiʻo mea mana ma ka iapaau ana o kekahi mau ano o intraabdominal a me ka pelvic nā mea palahēhē, a me palupalu'aʻaʻa nā mea palahēhē, iwi a me ka olelo nā mea palahēhē, septicemia.

I ka makaukau o ka ampicillin me ka sulbactam me ka nui loa aku ka hoʻokō like me ka amoxicillin / clavulanate ma ka iapaau ana o nā mea palahēhē mea i hoʻokumu pū atsinetobakterom.

Ke laʻau heluna o ka lāʻau e hoʻoholo i na olelo ao no ka hana. Ampicillin ua hoakakaia hōʻike waha, i ka mahele lāʻau no nā mākua mea ma 0,375-0,75 nā huna nānā 'ole o ka palaoa elua manawa iloko o ka lā, ina o ka maʻi, he mama külana. I oi loa ano o ka ka lapaʻauʻia hoʻohanaʻia 1.5-3.0 nā huna ma ka lā, i ka wa o ka oolea ua mahuahua, hiki e mahuahua ai ka laʻau heluna i 6.0 nā huna.

Mau keiki, lāʻau lawelawe i loko o nā māhele pōpilikia ma kahi o 50 micrograms no ka lā no kekahi kilogram o ke kaupaona ana o ke keiki. Komo ua lawe mai iʻelua wale nō.

Release palapala a me ka laʻau heluna o ka lāʻau wehewehe i au mamuli o ka olelo ao no ka hana. Ampicillin hiki ke lawe pū koe nae na papa ma ke ano o ka lepo hoʻohana, e hoomakaukau i ka kūikawā wehe (wā hōʻike waha lawelawe). A nae i ka hoʻohana 'ana i ka lāʻau ma ka pahu kui, no keia mea, ua hua mai la i ka pauka palapala. Ke'ūheheʻe lako me ka lāʻau i loko o ka hoʻokahi AEeAaOA.