"Zanidip": aʻo no ka hoʻohana 'ana, nā mea maʻi maoli a me na kahuna lapaau counterparts. "Zanidip-Rekordati": alakaʻi, hōʻike manaʻo, analogs

Wahi a ka 'ikepili helu, ma kahi o 26% o nā mākua i loko o ke ao nei e ae mai kiʻekiʻe ke koko, mau. Loa pinepine keia maʻi ua pili me ka aaiaoe predisposition. Eia naʻe, loaʻa nō nā kumu no kona hanana. O nā obesity, pūnuku puhi, excessiveʻai ana o ka paakai, nele o ka kumumea oihana mua a me nā wikamina i loko o ke kino, ka waiʻona hainā, stress, haʻahaʻa physical haʻawina, a me na mea e ae.

Ua E hoi e hoʻomaopopo i ka hooulu ana o ka hypertension hilinaʻi nui ma luna o ke kanaka o ka makahiki. O ka mua ia mea, i ke kiekie o ka pilikia ana o ia i ka pathological moku'āina. I ka makahiki o ka 40 makahiki, i ka maʻi i kokoke mau ka hopena o sclerotic vascular lesions.

kekahi mau 'ike

Loa pinepine, kauka i kā lākou nā mea maʻi i kaʻike, "nui hypertension". He aha ka mea? He He maʻi maʻi, a he kino o ka hypertension. Kona papa kuhikuhiE lapaʻau symptom hana paakiki, a hoʻolōʻihiʻia elevation ana o ke koko,.

Loli ma ia ano maʻi i e okoa. Naʻe, ka mea, kuhikuhi hai aku i na moku ke koko a me ka naau.

I mea e hoʻoikaika 'i ke ahonui o ka kanawai, kauka Meu i kēia lāʻau' like "Zanidip". Reviews o nā mea maʻi ma ka laulā o ka lāʻau, e e kūkākūkā i nā mea o kēia 'atikala. Pū ma lailaʻoe e loaʻa 'ikepili ma luna o ana i ka loaa mai la ka lapaʻauʻia, ina loaa ia ia kekahi analogues a me kaʻaoʻao' ole.

Description, haku mele 'ana, shape a me ka'ōpala

Ka medicament "Zanidip" aʻo ua waiho ia ma ka pepa laulau ua hookuu i loko o ka palapala o ka papa ho'ā melemele, a puni, a biconvex ano i ka hoailona ma kekahi o na aoao elua. Ka mea, e ho film-lole komoʻuʻuku nona, a i ka yellowish tint ma kaʻoluʻolu o.

Kaʻeleu 'Oponopono o keia k hana lercanidipine hydrochloride. Nō hoʻi, e nā a me kākoʻo eiiiiiaiou, a i na poe i povidone K30, lactose monohydrate, paʻakai carboxymethyl pia, microcrystalline kelulose a me ka makanekiuma stearate.

Me ka pili ana i ka ho film-ka penaʻana hoʻomanaʻo, a laila ka mea, ua haku o ka waiwai e like me Opadry Yellow, talc, hypromellose, titanium'okikene lua, hao'okesaside yellow kalameaʻai a me ka macrogol 6000.

Buy "Zanidip" huaale ma blister he huihui 'i e, i ka poe i waihoia ma ka pepa pahu.

Pharmacological ano o ka ai '

Aole anei oe i ike ia mea he lāʻau "Zanidip"? Na Ke Kumu ma o ka palapala noi i ka 'ia ia mea he kalipuna Kanal blocker lohi. Konaʻeleu 'Oponopono mea he racemic hui o ka dextro-a levorotatory stereoisomers. It E e kaulana no hoi ia ia mea he derivative o 1,4-dihydropyridine.

Kēia medicament selectively ka paleʻana papa o ke kalipuna Ion i loko o cardiac keena, vascular keena a me ka laumania Muscle.

I ka rula o ka malama aku antihypertensive kanawai o ka lāʻau mea pono i ka pololei relaxant kanawai ma vascular ala apuupuu Muscle keena.

E like me ka olelo, ma hope o ka loaa ana i ka pākōlea hopena o ka medicament ua loaʻa ma hope 5-7 hola. Ka lōʻihi o kona ho'ōia ua malamaia no ma ka lā.

Aie i ka selectivity kiʻekiʻe o ka lāʻau a hiki i ka vascular ala apuupuu Muscle keena, ka mea, 'aʻole i loaʻa ka io inotropic hopena.

No laila, ka mea i ka lāʻau "Zanidip-Rekordati"? Alakaʻi hākālia nō i ia mea metabolically'ākilikai hoolaia i mea ole i nui ole i ka maʻiʻo o apolipoproteins a me lipoproteins i loko o ke koko lāʻau lapaʻau, e like me 'aʻole e hoʻololi i ka holoʻokoʻa o ke kaikea i loko o kanaka me ka hypertension.

Nā kinetics o ka lāʻau

Where ke kemu lāʻau "Zanidip"? Na Ke Kumu no ka hoʻohana, e hai mai ia ma hope o ka loaa ana o ka papa (10 a 20 mg), maloko, lercanidipine kokoke loa o ke kemu, mai ka gastrointestinal'āpana. Mahope o 1.5-3 hola ka i kā mākou lehulehu o ka lāʻau i loko o ke koko, wai koko kīnā i ka waiwai o ka he 3.3 ng / ml paha 7,66 ng / ML niioaaonoaaiii.

Ka puunaue ana o ka lāʻau i loko o nā'aʻaʻa a me nā loko i wahiʻano koke. Palapala me ka wai koko nā polokina aku i 98%. Hai mahele lāʻau o na papa io o ko lākou hoʻomāhuahua ua malamaia.

Ke pūnao o ka lāʻau ua lawe mai i ke alahele mua ma ke akepaʻa. Kēia ia lŘlŘ ma biotransformation CYP3A4. Kēia hana o ka helu ana o metabolites a i ole pharmacological haʻawina.

E hōʻike 'lapaau "Zanidip", hōʻike manaʻo o ka mea i hōʻike mai iā ia iki emi ma ka naʻau liʻiliʻi a me nā puʻupaʻa. Aia nō nā kūlana ana o ka lercanidipine: i kakahiaka nui o kona manawa i ka 2-5 hola, a me ka hope loa - 8-10 hola.

Ka ua hoʻololiʻia lāʻau Ua kokoke i 'akomi i loko o ka feces a me ka mimi.

People me ka akepaʻa a me kaʻaʻa puʻuwai mai kumuʻiʻo maʻiʻo o ka wai koko ua me ka nui loa hoemiia. Ma keia manao, o ka noa hapa iki o ka hana waiwai o ka medicament i ke kūpono kou mahuahua.

Nāʻikepili e loaa ka lapaʻauʻia

No ke aha hiki e lanakila ka lapaʻauʻia "Zanidip"? Reviews o ka lapaau hōʻike i keia Agena kuleʻa hōʻike nō ia iho i loko o nui hypertension a me ka mehana e hoʻokanahaʻi oolea.

Contraindications e loaa i ka papa

E like me na kuhikuhi, ka lāʻau "Zanidip" E ole e ia ma lalo o ke ana ma lalo nei:

• loa ake hana;
• maʻi naau hoʻokō 'ole' ano (oi decompensation anu u);
• hihia hoʻiʻaʻa puʻuwai ho'āʻo;
• lolelua ka angina ;
• hui pu ana, a me nā mea kūpale ikaika isoenzyme CYP3A4 (no ka laʻana, "ketoconazole", "erythromycins", "itraconazole") a me "cyclosporin" a me ka grapefruit wai;
• i hāpai keiki;
• iaʻi o ka ipu koko e hele mai, mai ka ventricle hema o ka naau;
• lactose intolerance, lactase shortages a me malabsorption maʻi pale galactose / monakō koko;
• i breastfeeding;
• nei ma ka myocardial infarction (i loko o ka wā o kekahi mahina);
• Women o ka hanau keiki ana na makahiki o ka mea i ole hoʻohana ike loea 'ano o ka contraception;
• ma lalo o kona mau makahiki (hopenaʻoi loa a me ka maluhia i ole, ua hookupaaia);
• hypersensitivity e lercanidipine a me nā dihydropyridine nā mea loaʻa 'ole kekahi eiiiiiaiou o ka lapaʻauʻia.

Makaala lakou lawe ka lapaʻauʻia

Ka medicament "Zanidip-Rekordati" mālama nui ua? Aeiiaiaoaony e lawe kanaka me kaʻole ake papa (lōpū a me ka mehana), maʻi naau nedostatochnostyusindromom sinus, hema ventricular ka hoʻokō 'ole a me ka coronary artery maʻi, a me ka i ka wā hoʻokahi? Eaia "Digoxin" Hoʻokolohua-blockers.

Papa "Zanidip": kauoha no ka hoʻohana

Ma nānaina o ka helu nui o adverse hanana noʻonoʻo lāʻau pono e lawelawe ma ka hoao ana i nā limahana. Nō kāu, i kaʻeleu lāʻau ua? Aeiiaiaoaony e lawe i loko o ka nui o ka 10 mg koke i ka lā.

Akala e halihaliia oia iwaho i ke kakahiaka, no ka ¼ hola mua aina kakahiaka.

Ke kaumaha ma muli o ka pākōlea hopena o ka laʻau heluna o ka lāʻau ma lalo noonoo hiki ke papalua, a laila e pili ana i 20 mg. E hoʻoulu ai nā māhele o ka medicament e mākaukau i nā. Inā koi 'ia, ka mea ulu i loko o ka nui o ka medicament lawe mai ma hope o nā pule ma hope o he lālā o ka Inc.

Pehea lā au e lawe "Zanidip-Rekordati"? Mai a nau hou i ka papa. Ka mea, nui moni, a holoi iho la me ka lawa nui o ka wai.

Ma ka kūpuna No laʻau heluna hoʻoponopono ua koi 'ia. Akā, i ka wa e lawe ka lapaʻauʻia no lākou kulana pono maʻamau ka mālamaʻana.

Ma ke alo o hepatic aʻaʻa puʻuwai ka hoʻokō 'ole' ole lōpū dosages o ka umekaumaha? Iaea ua koi 'ia. Ma ka mea mua mau lā o ka lāʻau lawelawe i loko o ka nui o ka 10 mg, a laila, me ka mālama nui mahuahua ka mahele lāʻau a hiki i 20 mg no ka lā.

Inā ka antihypertensive hopena ua ikaika i olelo ia, ua hoemiia ka hoakaka laʻau heluna.

ʻaoʻao waiwai

Hiki i hua'ōlelo i makemake reactions "Zanidip-Rekordati"? Consumer hōʻike manaʻo hōʻike aku i kaʻai ana o keia mea ka mea, pinepine hōʻikeʻaoʻao ole. He aha kēia nui, ua noonoo pono manawa:

• 'ōnaehana paleʻea nenoaiu: Hypersensitivity.
• Mea'ōnaehana mānowai koko'ōnaehana: tachycardia, angina, palpitations, maʻule hou ihola nō, flushing i ka makaʻili, umauma eha, ia ka ho'ēmiʻana i loko o ke koko,, naau hoouka.
• Ko mākou hopohopo'ōnaehana: somnolence, headache, pōniuniu.
• Digestive'āpana: ka luaʻi, dyspepsia, nausea, reversible mahuahua ma ka akepaa nā'ūhū, diarrhea a me abdominal eha.
• Skin wikiwiki.
• Musculoskeletal nenoaiu: myalgia.
• Urinary: polyuria.
• Other:ʻike ākea edema, luhi, gingival hyperplasia, luhi.

Symptoms o overdose

He aha waiwai, e hahai aku, ina e lawe kiekie nā māhele o ka lāʻau "Zanidip"? Alakaʻi helu pū 'ia nā kēia symptoms o overdose: myocardial infarction, reflex tachycardia,ʻike ākea vasodilation me na hiohiona emi i loko o ke koko,, he mea ulu ma ka lōʻihi like' ole a me ka alapine (frequency) o angina ho'āhewa wale.

E hoʻopau i na Hawaii symptomatic lapaau.

lāʻau hana kūleʻa

Ua mea hiki, e hui pu iho la me nā ai 'lapaau "Zanidip"? Na Ke Kumu no ka hoʻohana i ka 'i ke koʻi lipi ua papaia e hui pu iho la me ia nā mea kūpale CYP3A4 (cytochrome P450 o ke akepaʻa), e like me "Itraconazole" "ketoconazole" a me ka "erythromycin". O ke kumu ho i ka mea i pau kēia mau laau lapaau hoomahuahua i ka lehulehu o ka lercanidipine i loko o ke koko, e like me kēpau i ka antihypertensive hopena.

I ka wā hoʻokahi? Eaia hōʻike 'ana no ia hoʻi i ka "cyclosporin" Ua contraindicated, e like me ka mea i alakai i ka hua ma ka maʻiʻo o nā waiwai i loko o ka hoʻomanawanui ka koko.

Lercanidipine ua pāpā 'ia e hoʻohana pu me grapefruit wai. Keia hui malu pu ana i ka hopena i potentiation o ka antihypertensive kanawai o ka lercanidipine a me ka inhibition o pūnao.

Ka mea, e hana lōʻihi mālama nui ana ka loaa ana "Zanidipa" me na ai 'like "Astemizole", "Terfenadine" a me ka "quinidine", a me kekahi antiarrhythmics o ke kolu o ka papa (e laʻa me, "Amiodarone").

Ke me ka hui pu ana o na noonoo medicament me anticonvulsant ai '( "phenytoin," Carbamazepine ") a me" rifamycins "e hoʻonui i ka ho'ēmiʻana i loko o ke koko o ka pae lercanidipine, kūpono i ka emi ana o ka antihypertensive hopena o ka lercanidipine.

A hiki aku i ka lāʻau me ka hui pu me ka "Digoxin" E noke kanaka hoʻoponopono na hoailona o ka intoxication.

I ka wā hoʻokahi lapaau me ka medicament "midazolam" ma ka adulthood e hoonui i ka absorbability o lercanidipine, a emi kona omo kōmi.

Poe akamai i aku nei au ia "metoprolol" Ua hiki ke hoemi bioavailability o lercanidipine 50%. Ma keia hihia, ke bioavailability o "Metoprolol" koe ua hoʻololiʻia. Keia kanawai kupu mai ka emi ana i loko o hepatic koko, kena ae la ia e Hoʻokolohua-blockers.

E hoomakaukau ai "Cimetidine" i loko o ka laʻau heluna o 800 mg no ka lā, mai ka hopena ma ka mea hou i loko o ke koko o ka lehulehu lercanidipine. Akā, ma kona? Eaia pono kūikawā mālama nui, no ka mea kiʻekiʻe nā māhele e hoonui i ka bioavailability o lercanidipine, a nolaila, e mahuahua ana kona antihypertensive ai.

Me ka hoʻohui pū 'ia o ka "Zanidipa" me "Simvastatin" ka mua lāʻau e e ia i loko o ke kakahiaka, a me ka lua - i loko o ke ahiahi.

Ka medicament "fluoxetine" i ole ia ma luna o nā kinetics o lercanidipine.

I ka wā hoʻokahi? Eaia "Zanidipa" me "warfarin" i i pili i nā pharmacokinetics o ka hope.

O na dala hiki ke hui me diuretics, Hoʻokolohua-blockers a me ACE nā mea kūpale.

Mākou E hoi e hoailona oukou i ka ethanol hoʻokāʻoi aʻe ana i ka antihypertensive hopena lekarnidipina.

kekahi koi

Uluwehi O "Zanidip", analogues o i i helu 'ia ma lalo iho nei, e noho me ka lōʻihi mālama nui i loko o kanaka me hihia hoʻi hakuʻala hana a me ka coronary artery mai, e like me ia ma keia hihia, aia no he pilikia nui o ka mahuahua alapine (frequency) o ke angina ho'āhewa wale.

Prior i ka loaa ana i ka lāʻau 'E mau ke compensated naau e loaa i kekahi maʻi maoli.

Mau mālama nui E e malama i ka hoʻomaka o ka Inc, o ka oi aku i loko o nā mea maʻi me ka lōpū a me ka mehana degere o hepatic insufficiency.

Ma lapaʻau, ka mea mea kupono e akahele lawe mai hana i ka pono kūikawā noonoo, a me ma ka alanui'ōnaehana. O ke kumu ho i ka mea e ma ka hoʻomaka o ke Inc, a me ka loa nā māhele he mea he pilikia o ka hanana o ke headache, drowsiness a me ka pōniuniu.

waho pūnaewele rula, o ka holopapa ola ana o ka la hoomalolo, a kuai

Where hiki I kuai huaale "Zanidip-Rekordati"? Analogs o na dala, oia ka lapaʻauʻia kuai i loko o kekahi drugstore. Naʻe, ka mea hiki ke kuai wale ma Kauka ka kuhikuhi.

E mālama i kēia lapaau mai o ka loaa ole makemake no ka bipi keiki ma kahi o ka mahana, aole ia i oi aku mamua o 30 degere.

Ke holopapa ola o ka lāʻau ma lalo noonoo o ekolu makahiki. Mahope iho o keia manawa, lalau iho la ka lapaʻauʻia ua pāpā.

lāʻau analogues

Anei oe i ike o ka mea e hiki ke kuapo huaale "Zanidip"? Analogues o keia mea paahana Ua paʻakikī e loaʻa. Poe akamai i hōʻike ua like ka waiwai a me ka hana ana o na hoomakaukau e komo me "Lerkamen" a me ka "Lercanidipine". Lālau aʻela kēia mau laau e wale ia no ka 'inikua'ōlelo aʻo.

Uluwehi O "Zanidip": hōʻike manaʻo o nā mea maʻi a me ka 'Oihana

He nui ka hoʻokō antihypertensive Agena. I keia manao ua kaʻana 'ia e na kauka. 'aelike' mākou me ia, a kokoke e pau loa nā mea maʻi e lawe huaale "Zanidip". Ka mea, koi ia ma hope o kona lawe ana i ka lapaau lākou kulana markedly hou. Na hoailona o ka nui hypertension ka mehana a me ka lōpū oolea haʻalele aneane koke.

Ka wale drawback o keia ka lapaʻauʻia ka i lawe ia loa pinepine ke kumu noʻaoʻao loa, o ka oi aku ma ka aoao o ka digestive'āpana, a me ka mea'ōnaehana mānowai koko nenoaia.

Ua E hoi e kaulana i na kanaka ohumu e pili ana i ke kumukuai o ka lāʻau mea, ua kiʻekiʻe. Kēia lāʻau i loko o ka huina o 28 papa hiki ke kūʻai no 450-500 rubles. It E e hoʻomaopopo i nā analogues o ka olelo mai medicament i loko o ka palapala o ka "Lerkamena" a me ka "lercanidipine" i hana ole ho'ēmi. Ka mea hiki ke kuai ia no ka mea hookahi uku.

Kilo'ōlelo aku nei au i ka waiwai e lilo aku ana o "Zanidip" antihypertensive lāʻau loa complies a me kona mea e like ai. Ua hōʻike kokoke i ka pau ana o kana hana lōʻihi i loko o ka palapala.