"Torasemide": olelo ao no ka hoʻohana. "Sandoz Torasemide": kuai, wahi, hōʻike manaʻo

"Torasemide" - he laekahi ikaika diuretic lāʻau i mea hemolele no ka lōʻihi-makahiki Inc o ka maʻi pili i ka helehelena o ka edema. Aie i ka mea uuku helu o clinically nuiʻaoʻao 'ole, i ka laula o kona pākōlea pono hou. He lua pele i 'ē aʻe loop diuretics, a ua oi hoike. Ma ka iapaau ana o ka maʻi likeʻole ka laʻau heluna ua Hoʻololi '. No hoi, ka mea i pono ma ka hihia o ka insufficiency o ka hakuʻala papa, a hiki ma ka haʻahaʻa kānana māmā holo glomeruli nephrons.

Waiwai "torasemide"

"Torasemide" like me ka 'elele loop (paʻakai) pae diuretics hana i loko o ka luminal hapa o ka epithelium o tubules o ka nephron i loko o ka pii aku ke kuleana o ka loop o Henle. Lawe 'ana i ka inhibitory ia ma luna o ka ami amo ana o potasiuma Ion a me ka paʻakai koloriside, ia me ka nui loa o ka electrochemical Loaʻaʻia ma kaʻilikai epithelium o ka nephron ho'ēmi i kā. Blockade hopena He hana maʻamau o ka ion amo paʻakai reabsorption mai ka iniiaiie mimi, a maoli he diuresis.

ʻaneʻane a pau loop diuretics i electrolyte haunaele aie i ka ikaika keiki reabsorption o potasiuma Ion, paʻakai, makanekiuma a me ka chlorine. "Torasemide" a hiki i ka uuku loa loli i ke koho ana o potasiuma a me ka makanekiuma, ma muli o ia a he nui haʻahaʻa mea hiki wale mai o arrhythmias, anorexia, constipation, Muscle nawaliwali. Nō hoʻi, i ka lāʻau a hiki i ka hōʻemi iki like ālai 'ho okumu o thromboxane A2, e holo ana na moku. He i ālai 'aldosterone receptors infarction, inhibiting na keʻano o ka hanaʻana o ka fibrosis o ka naau Muscle.

hoike

Pili ana i ka lāʻau "Torasemide" manual he 'ike e pili ana i ka maʻi, i aku la ia ia no ka iapaau ana. "Torasemide" ua hōʻike no:

• pathogenetic lapaʻau o arterial hypertension hoʻopale i ka Inc me ka hui pu ana o ka ACE nā mea kūpale (ARBs) thiazide diuretics;
• ka iapaau ana o ka maʻi naʻau ole, ke komo pū i ka circulatory overload koʻikoʻi a hanohano;
• symptomatic lapaʻau o ka maʻiʻaʻa puʻuwai 'ole, a me ke kānana i haahaa ka wikiwiki (emi o 20 ml \ min);
• symptomatic lapaʻau o ke akepaa (me ka pili hypoalbuminemia) edema like i kekahi koho e "Furosemide".

I ka hypertension "Torasemide" analogues a me generics i hoʻohana ma hope o ka hoʻokō 'ole o thiazide diuretics wale. A lāʻau hiki ke lawelawe ka lōʻihi no ka mea, o ka mea uuku helu o clinically nui a me ka weliweliʻaoʻao 'ole i loko oʻaʻa puʻuwai ole. Ka poe o ka "torasemide" Ua nui emi ma mua ia o ka "Furosemide".

Na Ke Kumu no ka hoʻohana

Ma muli o ka lapaʻau lula no ka lāʻau "Torasemide" manual maupaʻa na ano o ka lāʻau dosages koi 'ia no ka lapaau a me ka? Iaea o ka pale maʻi. Ma ke aha ka mea i loaʻa i loko o na papa i loaʻa i ka hahai nā mea hoʻohui i ka lāʻau ia iho: 2,5 mg, 5 mg, 10 mg, 20 mg, 50 mg, 100 mg, 200 mg.

E lawe i ka lāʻau ma luna o ka papa i loko o ke kakahiaka, ka nānā 'ana i ka palaoa. No kēia nā māhele o ka lāʻau "Torasemide" kumukuai okoa: ia mea ma lalo ma ka palena iki mahele lāʻau, a ma ka i kā mākou i ka lani kiekie loa. E like me kaʻawelike o ka aeaiiua, 30 na papa o ka lāʻau ma 5 mg e ma kahi o 400 rubles. I ka loaa ana keia mahele lāʻau e haawi like penei e like me na nāʻikepili:

• ma ka iapaau ana o ka hypertension ia 2,5 - 10 mg / lā;
• loaa 10-20 mg / lā no ka maʻi naau ole;
• maʻiʻaʻa puʻuwai ole - 50 mg a oi;
• ake ole pono kanaka mahele lāʻau ka hoʻoponopono '.

ʻaoʻao waiwai "torasemide"

Pili ana i ka lāʻau "Torasemide" manual he 'ike e pili ana i mauʻaoʻao ole. Ma ka pākōlea mahele lāʻau, oa mai i 200 mg no ka lā maoli i ka pilikia o thromboembolic complications, cardiac ischemia, cerebral. Ua maoli i ka pilikia o transient ischemic ho'āhewa wale a me myocardial infarction, pulmonary embolism, arrhythmias. Aia Ua hoi he pahiki o ka hanana o allergic rashes a hives ka wā o ka hoʻomanawanui ka predisposition.

"Torasemide" kekahi manawa ke kumu nausea a me ka luaʻi, kākaʻikahi mediate dyspepsia, diarrhea. Ho'ākāka 'ia ma kaʻawale hihia o ka pancreatitis i lapaʻau me "torasemide". Kekahi, a mahuahua nui hepatic transaminases, e hoike ana i akepaa kaʻawahia o ka lāʻau i loko o nā māhele kiʻekiʻe. I kekahi manawa, e hoomanawanui i hoohihiaia e pili ana i ringing i loko o nā pepeiao, blurred hihio.

Ka wā e loaʻa mai i kaʻawahia mahele lāʻau i loko o ka ulu 'moku'āina o overdose me ka uuku symptoms. Overdose ua pu ma ka lilo o ka loli ma ka mimi: diuresis lōʻihi a me ka pinepine, e ulu hypotension, vascular'opi, maʻule hou ihola nō, hahauʻana, cerebral ischemia i loko o ke kāʻei kua.

Contraindications a hoʻokau 'o ka palapala noi

Uluwehi O "Torasemide" analogues a me nōhie ai 'hiki ole e ia i loko o ke alo o ka loa contraindications. Mau mea i ka allergic naoh i ka lāʻau a me binders. "Torasemide" papaia e hoʻohana i kaʻaʻa puʻuwai ole me ka anuria, ake ole ana i loko o ka moku'āina o hepatic coma, me tachyarrhythmias. Contraindicatedʻai ana i lactation a me ka hāpai keiki, e like me ma lalo o ka makahiki o nā makahiki 18, hypersensitivity i sulfonamides.

ʻaoʻao a hui 'ole "torasemide"

Ma ka iapaau ana o ka hypertension huaale "Torasemide" hiki i ka hopena maikaʻi ia ma luna o ka papa o ka gout. Mai ka proximal tubules o ka nephronʻeleu waiwai kino ma kaʻeleu amo, he mea hoʻok & inhibition o excretion o uricʻakika. E kū'ē i ke kāʻei kua o ka pono o ka "torasemide" kiʻekiʻe pahiki o hyperuricemia a me ka huʻi gout.

Medicament "Torasemide" ua wehewehe aku ma kekahi mau 'ana ma luna o ka hapa proximal o omo epithelium loop o Henle. Aie i ka mea ikaika diuretic kanawai a me ka electrolyte imbalance keia kumu ka likelihood o clinically nui pharmacological hana kūleʻa. Ka mea, ua pilikia, mailuilu haalele a me ka mea i makemakeia. Mawaena o ka pilikia a me ka mea nui nō.

• kiʻekiʻe mahele lāʻau (50 mg / lā) "torasemide" ka wā hoʻohana i ka huipūʻana me ka platinum hoomakaukau ae hoʻokāʻoi aʻe ana i ka kaʻawahia o ka hope;
• nui nā māhele "torasemide" (50 mg / lā) hoonui nephrotoxic a me ototoxic hopena o ka aminoglycoside antibiotics;
• ma ka cephalosporin antibiotics, ka wā hoʻohana pū me "torasemide" i loko o ka mahele lāʻau o ka 50 mg / lā i Konakele. waiwai nephrotoxicity;
• salicylates pū me "torasemide" (50 mg / lā) wehewehe aku neurotoxicity.
• "Torasemide" e ku e ia i ke kāʻei kua o ka pili hypokalemia maoli ka susceptibility o ka myocardium i cardiac glycosides, mahuahua lākou inotropic a me ka antiarrhythmic hookoia, mahuahua i ka pilikia o kaʻawahia;
• ka pilikia o ka hypokalemia ua mahuahua ma concomitant ana "torasemide" me corticosteroids a Saline laxatives;
• "Torasemide" hoʻokāʻoi aʻe ana i ka hopena o ka "theophylline" curariform a me ka Muscle relaxants.

I makemake 'ole o ka hoʻohui pūʻia pono

No ka makemake ole e kauoha ka mālamaʻana, o ka emi i loko o ke koko, i lapaʻau me ACE nā mea kūpale. "Torasemide" ma muli o ia i ka wehe 'ia o ka loli ho'ēmi i kā ka hydrostatic puʻe o ke koko, e mediate i kekahi kulu i loko o ke koko,. Kēia kēia lākiō mea nui i loko o ka lapaau ana o hypertension a me ka pono? Iaea o ka mahele lāʻau o ACE nā mea kūpale. No hoi, ma ka iapaau ana o ka Inc-hoʻopale hypertension, a he huihui 'ana o ka ACE inhibitor "torasemide" e leie aku mākou i loaʻa ai i ke normalization ana o ke koko, i loko o 90% o nā mea maʻi.

Ma ka iapaau ana o ka maʻi naau hoʻokō 'ole' mea clinically nui hopena o ka hoemi i ka vasoconstrictor ha awina o catecholamines. Heart ma luna o ke kāʻei kua diuretic Inc "torasemide" nawaliwali pane aku ai, e stimulatory ÷ ailona adrenaline a me ka noradrenaline. Naʻe, ka mea e like me kanawai o ka hoemi i ka laulā o ka epinephrine a me ka norepinephrine i resuscitation.

Hopena maikaʻi 'ole o ka AaOIeIOUIeXAOAaIN

Aia waiwai inhibition hopenaʻoi loa ka wā hui me kekahi mau waiwai. I ka pau:

• hoomakaukau o ka bileʻakika sequestrants ho'ēmi i ka hopu "torasemide" o na naau oʻu, hoʻonāwaliwali i ke kanawai o ka hope;
• narcotic analgesics (NSAIDS) emi i ka laulā o ka "torasemide";
• "Probenecid" ma muli o ka amplification keʻano o ka hanaʻana urikozuricheskih inhibits koho "torasemide" i loko o ka lumen o na tubules, hoemi kona laulā.

Me nā 'ano "torasemide"

No ka hoʻomäkaukau ' "Torasemide" analogs hiki e ka papa, a me ka kinetic generics. Mawaena o ka papa poe analogues: "Furosemide", "bumetanide," "ethacrynicʻakika". I e like me ka "Furosemide" "Torasemide" ua wehewehe aku ma ka mea hookahi o ka hana, a me ka oi hooloihi ae i ia correlated me ka mahuahua diuresis. Ka hoʻolako 'diuretic ia mea kokoke i ka ia ikaika me ia o "Furosemide" "Torasemide" i poʻeʻuʻukuʻaoʻao' ole pili me ka kokololio electrolyte imbalance.

"Bumetanide" ua wehewehe aku e kekahi e oi aku diuretic ka waiwai i ua pili i na mea he nuiʻaoʻao ole. Ethacrynicʻakika i ka lalo hoouka kaua ana diuretic kanawai, a ua kākaʻikahi hoʻohana lāʻau. Nā pharmacokinetics o ka lāʻau "Torasemide" hōʻike manaʻo hoʻomalu ike i kekahi wahiʻano nui. Ka lāʻau i ka waiwai o ka "rebound": diuresis ma hope o amplification ma ka hoʻokaʻawale 'paʻakai i uku' kona ka mālama.

Pharmacokinetic analogues "torasemide"

Ka "Torasemide" ka lapaʻauʻia alakai hoʻolako 'ike ma luna o kona palapala noi i loko o nā mea maʻi me ka arterial hypertension. A me ka lāʻau, no ka lapaau ana o hypertension a me ka mea i hoʻohana thiazide diuretics, potasiuma-hookoe mai i kekahi. A thiazide manawa lohi e hele mai ana, a hooloihi ae i diuretic hooko i na ai 'o ka poʻe uʻi a.

Ma pili ana i kēia mau pharmacokinetic hiʻona analogues no ka hoomakaukau "Torasemide" noi paha ia i ka hahai: ka iapaau ana o ka hypertension, hoʻopale i ka maʻamau Inc me ka ACE inhibitor pu ana (a me angiotensin mea loaʻa blocker) me ka thiazide. No hoi, "Torasemide" ua hoʻohana 'ia i loko o maʻiʻaʻa puʻuwai ka hoʻokō' ole lapaʻau me ka ho'ēmi i kā kānana nona iho.

Generics "torasemide"

No ka hoʻomäkaukau ' "Torasemide" manual, analogues, nāʻikepili a me contraindications loa i emi iho kona papa kuhikuhiE ai - mahuahua diuresis. A, i kekahi hana i ka palapala lāʻau a me ka nōhie. Ka hope iloko o ka hookahi helu o "torasemide", akā, hua mai ma lalo o nā momoku ahi inoa.

Ua kaulana loa i: "Britomar", "Diuver", "Sandoz Torasemide", "Trifas", "Torcida", "Trigrim". I nui ikea ai o pharmacological Luna nui oko ao i malamaia ma waena o ia i loko o Rusia. Kēlā me kēia o ka mea ma luna o mea haʻilula keimikala loa replaces ka'ē aʻe o lākou.

Aneiai, ao ke ano o ka lapaʻau "torasemide"

Ma ka iapaau ana o hypertension ka wā o ka thiazide diuretics i ineffective ma ka hui pu ana, me ka ACE nā mea kūpale (a ARBs), hiki ke lawelawe lāʻau lapaʻau "Torasemide": kuhi no ka hoʻohana hoʻopaʻapaʻa hookahi mahele lāʻau i ka lā. Ka malama kāki o ka lapaʻau mea e pili ana 400 rubles ma ke kumu kuai o ka 60 o na papa io o ka lāʻau ma kahi o 760-800 rubles. No ka nane hea, ka mea malama kumukuai o ka lapaʻau "Furosemide" kākaʻikahi mamua o 20 rubles. Akā, i ka la mahope no ana hana o ka hypertension mea o ka uuku ana.

I ka maʻi naʻau ole me ka edema o nā pōʻai holo kāki o ka malama lapaʻau "Furosemide" mea e pili ana i 20-30 rubles. No ka hoʻomäkaukau ' "Torasemide" kumukuai mea 10-15 manawa oi aku. Ka hope i ka mehana keia, i mea immaterial maoli ka excretion o ka mimi ana ma na hora mua o ka hiki aku. Ka "Furosemide" ano o ka aʻe: ia nui maoli ka nui o ka mimi i loko o ka mau hola mua me ka gradual mea hoʻonāwaliwali maoli nō o ka mimi ia auoiaea.

E like me ka hopena, employable nā mea maʻi me ka hypertension a maʻiʻaʻa puʻuwai insufficiency a circulatory reasonably pili "Torasemide" aʻo (kona kumukuai i hōʻike ma luna) ma luna o ka palapala noi a kekahi mau 'ike e pili ana i ka nui holomua o diuresis i loko o ka manawa mua o? Eaia. Naʻe, ka mea hoohuoi ia makahiki o nā mea maʻi i loko o ka wa e kaawale aku o ka pono e hiki mai ana i ka hana, mimi auaiaea Aloha; he aneane pili '. Ia, aole ia e hana pilikia, a no ia mea, e leie aku oe, e loaa i ka nike papa mea like - "Furosemide".