'ākilikai phosphatase - nui i'ūhū ke kanaka kino

I ka lā, i ka luna 'ʻike, o ka maʻi he nui i hoʻohana keʻena hoʻokolohua ki ina hana like o ka ninaninau. Ua komo ai i ka biochemical Ka Ikepili o ke koko.

'ākilikai phosphatase: mau 'ano o ka'ūhū

'ākilikai phosphatase - kekahi o ka mea nui nā hoailona. Kēia hui o ka'ūhū i hōʻike phosphatase hope. He makana i loko oʻaneʻane pau kanaka keena. Kona i kā mākou hana ua hoike mai ia ma ka'ākilikai meakino, a ua pili i aeea membranes. I ka lani kiekie loa lehulehu o keia hui ua kākau i loko o osteoblasts (keena ma ka iwi'aʻaʻa), ake keena a me kaʻaʻa puʻuwai tubules ma ka intestinal mucosa, e like me ke keiki. 'ākilikai phosphatase, i ua iloko o loko o ka lāʻau lapaʻau, e like me ka rula, loko mai ka iwi a me hepatocytes. Kona kiʻekiʻe ha awina ua malamaia kuhikuhi ma ka ake maʻi e hana me ka iaʻi o ka bile leki uea, e like me ka lesions o ka iwi i pu ma ka iwi remodeling.

'ākilikai phosphatase ilikai mea kiʻekiʻe. No ke aha?

He nui maʻi Hawaii ma i māhuahua'ākilikai phosphatase. Ke kūmau o keia anakahi hilinaʻi nui ma luna o ka makahiki a me ke keka, no laila lawe i kēia i loko o ka wā no ka unuhi koko biochemistry.

Mawaena o ka etiological aʻe i ke loli ka nui o nā'ūhū, a me kona'ākilikai phosphatase, e like me ka mea kēia:

• hāpai keiki;

• Postmenopausal;

• lawaʻai ana o dietary kalipuna, a me phosphates;

• oi o ka ascorbicʻakika i loko o ke kino;

• ka hoʻohana o hookahi pharmacological Luna (e laʻa me, contraceptives i loaʻa ka estrogen a me ka progesterone, e like me antibiotics).

Eia hou, hiki e mahuahua kona'ākilikai phosphatase i loko o ka maʻi i kēia:

• hyperparathyroidism;

• naau pepehi hakuʻala paha akemāmā'aʻaʻa;

• mau myeloma;

• infectious mononucleosis;

• iwi maʻi, me Ka maʻi 'aʻai o keʻano;

• Hodgkin ka maʻi, a ia lŘlŘ me ka luku ana o ka iwi;

• rickets;

• malignant lesion o biliary'āpana;

• li nui o ka infectious 'ano' ole cirrhosis o ke akepaʻa, kona pio tuberculosis.

Etiology emi'ākilikai phosphatase

Aia nō i ka helu o ka pathologies ma i, ma ka mea ku ole,'ākilikai phosphatase hoemiia. Penei, o ka nui o ka'ūhū lalo maʻamau ma ka hypothyroidism. Kue o ka iwi a ulu, deficiency o kiniki a me ka makanekiuma, e like me anaemia - etiological aʻe i ke loli ka nui o kona'ākilikai phosphatase i loko o ke koko lāʻau lapaʻau. E lawe i kekahi mau lapaʻauʻia i hoololi ae i ka hoao ana i nā hualoaʻa. Eia kekahi, i ke alo o ka puʻupuʻu, a hoʻomōhala i ka aie i ka insufficiency o ascorbicʻakika hiki aku ai i ka emi ana o ka'ūhū.

It E e kaulana ia ma ka hāpai keiki'ākilikai phosphatase hiki ulu ma ka hoʻoulu i ka helu o placental isoenzyme. Kēia mea typical o na kahua o ka hoʻonaʻauao hope loa o ka hāpai keiki, a ua pili i ka mea i kā mākou kūpono 'ana o ke keiki. Oia kekahi kumu i ole PalekanaEND_LINK waiwai, no laila ia mea e kū ana no ka loiloi 'ana i ka moku'āina o ka makuahine, a me fetus. Ma na hihia i ka wa a ka wahine ua diagnosed placental insufficiency, ua hoemiia ka lehulehu o keia hui'ūhū.

Hiʻona o ka loli ana o ka nui o kona'ākilikai phosphatase

'ākilikai phosphatase mea ma ka palapala o kekahi mau isoenzymes. Ke degere o ka mea ulu i loko o ka lehulehu o ka hui ua correlated me kaʻeleu osteoblastic (iwi ho okumu kaʻina), no laila, i ka mea o nā kulanui o ka iwi isoenzyme malamaia ma Paget ka maʻi. Inā ka hoʻomanawanui e hoʻomōhala ana i ka pathology me ka osteolytic ha awina (e like, mau myeloma), ka'ākilikai phosphatase māhuahua, akā, wale iki.

I ka lesions o ka hepatobiliary'ōnaehana maoli he hepatic isoenzyme. Ma lapaʻau hana, ka mea, ua hoʻohana 'ia me ka peni mäka o cholestasis. Ma keia hihia, me ka pololei poho o ke akepaʻa aeee ke lawe wahi e ku e ia i ke kāʻei kua o ka maʻamau 'ole i haʻahaʻa pae o'ākilikai phosphatase. Kēia kumu, ua typical, like me ka rula, no ka hapanui lapaʻau hihia, eia nae ka mea hiki ole ke malama i loko o kekahi kanaka hoomanawanui, a hiki i poho i ke akepaʻa a me biliary'āpana.

Ua mea waiwai 'ana i kumumanaʻo ua hoonuiia ae kona'ākilikai phosphatase i loko o ke keiki - he physiological kŰia, a ua pili i ulu ikaika. Penei, o ka nui o keia'ūhū i loko o na keiki i hiki i ka 'ilikai a aku i ka kūmau no ka makua kanaka mea 1.5-2 manawa (mai ka 82 a hiki i 341 U / L).

Specificity hoomaopopo ana i ka nui o kona'ākilikai phosphatase

I ka lā, he okoa ka mea e pono ai ke olelo i ka Ikepili ma ka manao paa o ka lehulehu o kona'ākilikai phosphatase, no ka mea, kēlā me kēia keʻena hoʻokolohua i kona mau hae. Aia i kekahi mau mea o loko ano i hilinaʻi ma ka'ūhū kūpapakū a me ka aooa?'ōnaehana like hoʻi me ka mea ana wela ma a ka Eia kekahi laʻana i paa. Pahele palena anakahi "kona'ākilikai phosphatase" mea ole, pela no ia mea,ʻaʻole e pono e hoohalike i ka aiee o ka'ūhū, i i loaa i loko o kekahi keʻena hoʻokolohua. He mea oi loa aku hoi oiaio ia mea, ua ole ikea ka rula mau keʻena hoʻokolohua hoʻonoho.

No Ka Ikepili o ke koko lāʻau lapaʻau ua hoʻohana 'ia. Ma ka hapanui o na hihia, e lawe ana i ka luna, ahu iho, i ka mea i hanaʻia i loko o ka separator Tube. Ua mea waiwai 'ana i kumumanaʻo ana i ka nui o kona'ākilikai phosphatase i ke erroneously mahuahua, ina i ke koko mea hōʻikeʻikeʻuʻuku tourniquet ma ka hoaka o ka lala i kau ai no ka oi mamua o 30 kekona. Eia hou, i ka ha awina o keia'ūhū i ĸokoĸa ana nä pane iki ina i ke koko hāpana i waiho ai i mehana ea. Ma keia ma lūmaua hemolysis 'aʻole i pili i ka hoao ana i nā hualoaʻa.

He aha e hana ia i ka pathological kiʻekiʻe o kona'ākilikai phosphatase?

I ka kona'ākilikai phosphatase nui ae, i ka iapaau ana pono i etiological ao ao. Penei, i ke alo o ke akepaʻa a me biliary maʻi e nīnau i ka gastroenterologist. Cholestasis, imua pancreatitis, kanakaʻona mau hepatitis a cirrhosis pono AYEIE? Iaea lāʻau nona ka leo e wale nānā 'ia e ke kauka. Iho i loko o keia hihia ke alakai i ka aggravation o ka iniiaiie maʻi.

Hoʻololi i ka lehulehu o nā'ūhū, a me kona'ākilikai phosphatase, hiki ke mālama i loko o ka naʻau o ka hoʻokō 'ole,' aʻai pathology a me ka loa poino i nā puʻupaʻa, e like me ka pono me ka mimikō, pela no oe e nīnau aku i ka cardiologist, nephrologist paha endocrinologist. Ke Kauka e ho oholo i ka pākōlea nā kaʻa mokulele ke kaumaha ma muli o ka lapaʻau kiʻi.

Ma ka wehe i ka etiological kumumea,'ākilikai phosphatase hope hoi i ka maʻamau. Ma ke kauoha o ka Inc E e ia i loko o ka mea ana, no ka laʻana, he physiological mahuahua o keia anakahi mea hiki i fractures,ʻeleu ulu o ka skeletal oihana, me ka gestation. Ua 'Aʻole e koi' inikua 'uao. Ano o ka hopena o ke keʻena hoʻokolohua e ho'āʻo ai e halihaliia oia iwaho comprehensively, e lawe i ka mooolelo'ē aʻe biochemical kiko'î a me ka hoʻomanawanui, hoopii.