'O ke Kaupīpī'Oi'o: nā kuhikuhi no ka ho'ohana a me nā hō'ike

'O nā lālā kū'ai lā'au hō'ailona hana i ka nui o nā lā'au antiepilepic. Pehea e maopopo ai i ke'ano o nā lā'au lapa'au? No ka hana'ana i kēia, pono'oe e kelepona i kahi mea loea'ike. Hiki iā ia ke koho i ka lā'au lapa'au loa no'oe, a laila e kōkua i ka hana nui o ka ma'i o ka mea ma'i.

'O ka lā'au lapa'au lapa'au kaulana loa i waena o nā ma'i a me nā kauka he lā'au hō'ona "Primidon". Nā kuhikuhi no ka ho'ohana'ana i kēia lā'au lapa'au, e waiho'ia ma lalo nei kona'ano ho'oku'u a me nā waiwai.

Ka hana, ke'ano a me ka hō'ailona

Hiki iā'oe ke kū'ai i ka lā'au "Primidon" i nā'ano like'ole. Hiki ke loa'a i loko o ke'ano o ka pauka, kahi i ho'okomo'ia i loko o kahi'eke lua-'elua a me ka pahu pahu pahu polyethylene. Eia kekahi, hiki ke kū'ai'ia kēia lā'au lapa'au ma ke'ano o nā papa i nā pu'u a me nā pahu pahu.

'O ka mea hana hana o kēia lā'au lapa'au ke kumu. Ho'ohui pū'ia nā mea kōkua (e pili ana i ke'ano o ka ho'oku'u'ana).

Nā lā'au lawelawe

He aha ka lā'au "Primidon"? Ke kuhikuhi nei nā kuhikuhi no ka ho'ohana'ana i kēia luna antiepileptic. Hā'awi ia i ka hopena o ke kalapiko me ka ha'aha'a i'ōlelo'ia, a ke emi nei ka mea nui o nā neurons, aia i loko o ka māhele epileptogenic.

He aha nā'ona'ē a'e i komo i loko o ka lā'au "Primidon"? He mea nui loa, ho'opau'o ia ma ka ho'onāukiuki'ana i ke koko i kahi 12 μg / ml.

Nā mea Kinetic

'O ka lā'au'a'ala "Primidon" (mau papa a me ka lepo) ua wikiwiki a aneane e ho'opau loa'ia mai ka'ōhumu'ōpala. Ho'omaopopo ka nui o ka ho'ohana'ana i kēia lā'au i hope o'ekolu hola. 'O ka loa'a'ana o ka lā'au olaola he 90-100%. I ke koko, pili pili i nā proteins (e like me 20%).

'O ka hapalua o ke ola o kēia ho'oponopono he 7-15 mau hola.

I loko o ke ake, ho'ololi'ia ka lā'au lapa'au i phenobarbital (e pili ana i 20%) a me phenylthylmalonamide. Hana kēia mau mīkini i ka hana antiepileptic. Ho'opuka'ia e nā pu'upa'a.

I ke koko o ka mea ma'i, pono pono ke mālama i kahi kaukau lā'au lapa'au o 12 μg / ml. 'O kēia mau'ano e hāpai i ka ho'ēmi'ana i nā hopena ho'onāukiuki. I kekahi mau hō'ike'ē a'e o ka ma'i'ehā (e like me ke'ano o ka hō'eha'ole, nā'āpana polymorphic a me nā mea'ē a'e),'a'ole i loa'a mau'ia ka hopena o ka lā'au. I kēia kūlana, he mea pono ka ho'oma'ama'a'ana.

Nā kuhikuhi e ho'ohana ai i ka lā'au lapa'au

I nā nīnau hea i hā'awi'ia ai ka lā'au ma'i e like me "Primidon"? Ke'ōlelo nei nā hō'ike he ho'oponopono maika'i kēia ma'i i nā epilepsy o nā'ano like'ole, a me ka hopu'ana i ke'ano a me ka'ike'ole. Me ka ho'oikaika'ana i nā mea kūpono, ka myoclonic, a me ka hō'eha kino,'a'ole i'oi loa ka maika'i o kēia lā'au.

Nā kuhiakau i ka lawe'ana i ka lā'au

I kŰia mau kumu, kŰia mea e kau ole i ka laau "Primidon"? 'O ka'ōlelo a'o no ka ho'omaopopo'ana'a'ole hiki ke ho'ohana'ia kēia ho'oponopono i mua o ka hōkuli'ana (pēlā i ka barbiturates), a me ka anemia, ka hepa, a me ka lawa'ole, ka hāpai, leukopenia a me ka hānai.

'O ke Kaupona Medid: kuhikuhi no ka ho'ohana'ana

Ma ke'ano hea ke'ano lā'au lā'au a mākou e no'ono'o nei? Lawe'ia i ka waha ma hope o ka'ai'ana i ka mea'ai i ho'okahi wale nō mau'ano 125 mg. Ma hope o kēia, i kēlā me kēia lā'ekolu, ua ho'onui'ia ke ola o ka lā'au i 250 mg no nā po'e mākua a me 125 mau keiki no nā keiki i hiki i ke 9 makahiki.

Ho'omau'ia kēia ho'olālā a hiki i ka hopena o ka hopena i makemake'ia.

'O ka lā palena ma'amau o ka lā'au lapa'au no nā keiki he 1 g (ma nā'oko'a'elua i māhele'ia), a no nā mākua - 1.5 g.

Nā Hua'ao'ao

Akā,'o ka lā'au antiepileptic i no'ono'o pinepine'ia e ho'oulu i nā mea e pono'ole ai. 'O kēia mau mea he nui o ka hiamoe, ka na'au hina, ka no'ono'o, ka maka'u, ka mana'o'ole, kausea, ka anemia, ka lua'i'ana, leukopenia, nā hopena ma'i a me nā lymphocytosis.

'O ka mea ma'amau, hiki i kēia lā'au lā'au ke hō'eha i nystagmus, ataxia, "lupus" syndrome, nā ho'oikaika o ke aloha o ka na'au, ke ake'ana, meemia megaloblastic, a me ka ho'olō'ihi o ka ho'ohana'ana i ka lā'au.

Nā hihia ho'olimalima

'O ka hopu'ana i nā lā'au nui o ka lā'au lapa'au e hiki ai ke ho'oholo i nā hō'ailona like'ole dizziness, ataxia, nausea a me ke kaumaha o ka CNS. No ka mālama'ana i kēlā'ano kūlana, holoi'ia ka mea ma'i me ka'ōpū, ka papahu i hana'ia a hō'ike'ia i nā lā'au ma'amau.

Ho'ohui me nā lā'au'ē a'e

'O ka lā'au lapa'au "Primidon" ke ho'onui i ka hana o cyclophosphamide, sulfonylureas a me methotrexate, a me nā hana hau. Hiki ke ho'oikaika i ka mīkini kahe, ho'onui i ka hana o nā enzymes o ka'ōiwi microsomal, e ho'onā i ka hopena o GCS, paracetamol, ISS, mau antidepressants tricyclic, antioagulants ala'ole, Chloramphenicol, Dacarbazine, Cyclosporine, glycosides cardiac, Dizopiramid, Levothyroxine, Doxycycline "," Theophylline "," Metronidazole "," Quinidine "," Mexiletina ", ka hua'a D," Fenoprofen ", ka kalo," Aminophylline "a me" Oxtryphylline ".

'O ka lā'au lapa'au e no'ono'o ana e ho'onui i ka mana'o kaumaha o ka CNS i ka hui pū'ana me nā lā'au lapa'au me kahi mea pilikia a me ka mea inu.

'O ka lā'au'awa'au "Amphetamine" e ho'onōlie i ka lawe'ana o phenobarbital.

Ma ka hui pu ana me ka carbonic anhydrase nā mea kūpale listen osteopenia.

'O kēia lā'au lapa'au e ho'ēmi i ka lawe'ana o griseofulvin, a hiki i ka emi'ana o kāna hana hana. Ho'onui'ia ka hopena o "Enflurane", "Methoxyflurane" a me "Harani".

"Methylphenidate" e kōkua i ka ho'opau'ana i ka kinakolism o ka primodone a ho'onui i kona kūmole ma ke koko.

"Leucovorin" ma nā mea nui e ho'onāwaliwali i ka hopena anticonvulsant o primidone. Ho'ohana kēia i ka lā'au lapa'au "Phenylbutazone".

Nā Kūkākūkā Kūikawā

'O ke lā'au lā'au "Primidon" hiki ke ho'ohana'ia i ka ho'oponopono āpau o ka anticonvulsant. Ke ho'opau'ia'ana, e like me ka ho'ololi'ia o kēia lā'au lapa'au e lawe'ia ma ka li'ili'i.

Me ke'ano kūikawā, ua kauoha'ia nā mākua a me nā kānaka nāwaliwali. Me ka ho'omohala'ana o ka anemia megaloblastic, ho'opau'ia ka lā'au lapa'au a kauoha'ia e mālama me ka lā'au'o B12 a me ka waikawa paila.

'O ke'ano kēia e ho'ēmi ai i ka mana'o o ke kanaka psychomotor. No laila,'a'ole ia e hā'awi'ia i nā ho'okele ka'a a me nā po'e i hana like me nā mea ho'one'e.

Me ka ho'omana'o, ho'ohana'ia kēia lā'au lā'au i nā keiki.

Ke'ano like

He aha ka'u e pani ai i ka lā'au "Primidon"? Hiki ke kū'ai'ia nā analogues o kēia mea hana ma kēlā me kēia kākena a i kauoha'ia paha ma o ka Pūnaewele puni honua.

Wahi a ka po'e akamai,'o nā lā'au like "Hexamidine", "Benzonal" a me "Phenobarbital" kekahi mau'ano like.

Nā Niko Pa'i

'O nā mea nāna e lawe i kēlā lā'au lapa'au pīpīpile e like me "Primidon" waiho wale i nā pane maika'i no ia mea. Wahi a kā lākou hō'ike'ana, kū pono kēia lā'au lapa'au me kāna'oihana. Ke kāohi nei ia i ka hopena o ka hopu'ana a me ke ka'ina. 'O kēia mau lā'au lapa'au ke kōkua i ka hō'emi'ana i nā hō'ailona o epilepsy.

No nā loiloi maika'i, kokoke iā lākou a pau e hō'ike ana he ulu kēia lā'au lapa'au i ka hopena o ka hopena o nā hopena. No laila,'o ka ho'ohana'ana i ia lā'au lapa'au wale nō ia no ke kauka'ana o ke kauka.